PRCC/MDACC: Partners for Excellence in Cancer Research

PRCC/MDACC：癌症研究卓越合作伙伴

• 批准号: 6488638
• 负责人: Gabriel Lopez-Berestein
• 金额: $ 79.38万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-16 至 2007-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6488638
• 关键词: Hispanic Americans; behavioral /social science research tag; clinical research; cooperative study; genetic susceptibility; health services research tag; human subject; medically underserved population; minority institution research support; neoplasm /cancer; neoplasm /cancer education

Significant disparities in cancer incidence and outcomes exist among ethnic minority populations. The overall Goal of this U54 Application is to establish a comprehensive long-term mutually beneficial partnership between the University of Texas M.D. Anderson Cancer Center (MDACC) and the University of Puerto Rico Cancer Center (PRCC). This partnership was initiated three years ago through the support of a supplement to MDACC P30 grant. Specific Objectives of the current proposal include: a) development of independent cancer research investigators through collaborative research projects, and b) establishment of a stable, long-term mutually beneficial collaborative relationship between MDACC and PRCC in the areas of cancer research, training and education. Efforts will be focused on the following areas: 1) Cancer research: the major programs and pilot projects address (a) molecular epidemiology of Head and Neck Cancer, and Breast Cancer, (b) cancer biology related to Breast Cancer, and (c) areas of cancer disparity in minority populations such as Acute Pro-myelocytic Leukemia; 2) Cancer Research training and education programs are described for undergraduate, graduate and post-doctoral students in areas of Cancer Biology, Outreach, and Epidemiology. PRCC and MDACC will continue the establishment of a comprehensive bi-directional training program that will increase the number of Hispanic students interested in cancers in cancer research. In addition, PRCC faculty will receive research training at MDACC; PRCC faculty will increase sensitivity of MDACC faculty to cultural differences among Hispanic groups, a particularly important benefit as Houston's and Texas's Hispanic population continues to grow. Infrastructure activities will include the frequent use of video conferences, library services support, and establishment of a tissue bank. Outstanding individuals agreed to serve as internal advisors and in the Program Steering Committee. The partnership will enhance the opportunities of both institutions to apply for R01s, SPORES, PO1s and R25 Cancer Education grants with an emphasis on reducing cancer disparities among populations. Finally, one of the major long-range goals of the partnership is for PRCC to regain its status as an NCI-designated Cancer Center.

少数族裔人群的癌症发病率和结果存在显着差异。此 U54 申请的总体目标是在德克萨斯大学 M.D. 安德森癌症中心 (MDACC) 和波多黎各大学癌症中心 (PRCC) 之间建立全面的长期互利合作伙伴关系。这一合作伙伴关系是在三年前通过 MDACC P30 补助金补充支持启动的。当前提案的具体目标包括：a) 通过合作研究项目培养独立的癌症研究人员，以及 b) MDACC 和 PRCC 在癌症研究、培训和教育领域建立稳定、长期互利的合作关系。工作重点将集中在以下领域：1）癌症研究：主要计划和试点项目涉及（a）头颈癌和乳腺癌的分子流行病学，（b）与乳腺癌相关的癌症生物学，以及（c）少数群体中癌症差异的领域，例如急性早幼粒细胞白血病； 2) 为癌症生物学、外展和流行病学领域的本科生、研究生和博士后描述了癌症研究培训和教育计划。 PRCC 和 MDACC 将继续建立全面的双向培训计划，以增加对癌症研究感兴趣的西班牙裔学生的数量。此外，PRCC 教师将在 MDACC 接受研究培训； PRCC 教师将提高 MDACC 教师对西班牙裔群体之间文化差异的敏感性，随着休斯顿和德克萨斯州西班牙裔人口的持续增长，这是一个特别重要的好处。基础设施活动将包括频繁使用视频会议、图书馆服务支持以及建立组织库。杰出人士同意担任内部顾问和项目指导委员会成员。此次合作将增加两家机构申请 R01s、SPORES、PO1s 和 R25 癌症教育补助金的机会，重点是减少人群之间的癌症差异。最后，此次合作的主要长期目标之一是让 PRCC 重新获得 NCI 指定癌症中心的地位。