BIOMEDICAL IMAGING RESEARCH NETWORK

生物医学成像研究网络

• 批准号: 6768273
• 负责人: Mark H Ellisman
• 金额: $ 405.72万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-26 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6768273
• 关键词: Internet; bioengineering /biomedical engineering; bioimaging /biomedical imaging; bioinformatics; brain imaging /visualization /scanning; computational biology; computer program /software; computer system design /evaluation; computer system hardware; cooperative study; information systems; nervous system disorder; neuroimaging

DESCRIPTION (provided by applicant): The Biomedical Informatics Research Network (BIRN) is a recently-launched initiative to foster large-scale collaborations in biomedical science by utilizing the capabilities of the emerging national cyberinfrastructure (high speed networks, distributed high-performance computing and the necessary software integrative capabilities). Scientists at the San Diego Supercomputer Center and the School of Medicine at the University of California San Diego (UCSD) serve as the BIRN Coordinating Center (BIRN CC) for this large project. The BIRN CC serves the critical task of developing, deploying and maintaining key infrastructure components, including high bandwidth connectivity via Internet 2, Grid-based security, file management and computational services, techniques to federate databases and shared visualization and analysis environments. In its initial phase, the BIRN involves a consortium of 12 universities participating in test bed projects centered around brain imaging of human neurological disorders and associated animal models. Groups are working on large scale, cross-institutional imaging studies on Alzheimer's disease, depression and schizophrenia using structural and function MRI. Others are studying animal models relevant to the study of multiple sclerosis, attention deficit disorder, Parkinson's disease and brain cancer using MRI, whole brain histology and high-resolution light and electron microscopy. The BIRN CC provides the focal point for interactions among the BIRN partner sites, both coordinating and catalyzing the successful collaboration of a large group of highly talented scientists. This proposal describes continuation plans for the BIRN CC for the next five years. In the next phase, the BIRN CC will continue to support and enhance the existing infrastructure while fostering and facilitating collaboration among the BIRN participants. Development and implementation of new technologies will continue to be tightly coupled to the requirements of the various test bed projects and will be informed by lessons learned during the initial phase. At the same time, the BIRN infrastructure will continue to evolve in accordance with emerging Grid standards, anticipating the longevity and future expansion of the BIRN.

描述（由申请人提供）：生物医学信息学研究网络（BIRN）是最近推出的一项计划，旨在通过利用新兴的国家网络基础设施（高速网络，高速度网络，分布式高实行计算和必要的软件集成能力）来促进生物医学科学的大规模合作。圣地亚哥超级计算机中心和加州大学圣地亚哥分校（UCSD）医学院的科学家是这个大项目的BIRN协调中心（BIRN CC）。 BIRN CC服务着开发，部署和维护关键基础架构组件的关键任务，包括通过Internet 2，基于网格的安全性，文件管理和计算服务，用于联合数据库的技术以及共享可视化和分析环境的技术。在最初的阶段，BIRN涉及由12所大学参与围绕人类神经系统疾病和相关动物模型的大脑成像的测试床项目的联盟。通过结构和功能MRI进行大规模研究，关于阿尔茨海默氏病，抑郁和精神分裂症的跨机构成像研究。其他人正在研究与多发性硬化症，注意力缺陷障碍，帕金森氏病和脑癌的研究有关的动物模型。 BIRN CC为BIRN合作伙伴网站之间的互动提供了焦点，这是协调和催化一大批才华横溢的科学家的成功合作。该提案描述了未来五年内BIRN CC的延续计划。在下一阶段，BIRN CC将继续支持和增强现有的基础设施，同时促进BIRN参与者之间的合作和促进。新技术的开发和实施将继续与各种测试床项目的要求密切相关，并将通过初始阶段中学到的教训来告知。同时，BIRN基础设施将根据新兴的网格标准继续发展，预计BIRN的寿命和未来的扩张。