COBRE: RIH:CORE A: ADMINISTRATION & CAREER DVMT

COBRE：RIH：核心 A：管理

• 批准号: 7381870
• 负责人: Douglas Carter Hixson
• 金额: $ 40.13万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381870
• 关键词: COBRE; RIH; CORE; ADMINISTRATION; CAREER

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The mission of the CCRD is to create, interpret, and apply new knowledge based on original, collaborative, multidisciplinary laboratory studies of the cellular and molecular pathways leading to gastrointestinal cancer. This broad area of research is represented by investigators pursuing research relevant to four major themes - Theme A - The significance of fetal proteins and phenotypes in Cancer; Theme B - Pathogenesis Of GI Tumors; Theme C - Signal Transduction Mechanisms Relevant to Carcinogenesis; Theme D - Role of RNA and DNA Viruses in Cancer. Over the last four years, the scope of research supported by the CCRD has broadened beyond gastrointestinal cancer and now includes projects examining molecular events relevant to breast, prostate, kidney and lung cancer. To reflect this change in scope and to emphasize the translational potential of ongoing research, our overall theme will now become ¿Molecular Targets for Cancer Intervention¿, a theme that engenders a broader vision of basic research that we feel will encourage investigators to find creative ways to translate new insights into the molecular basis of neoplasia into improved methods for diagnosis and treatment. Possible sub themes being considered include: Biomarkers for predicting response to therapy, prognosis, staging; Targets for molecular intervention using siRNA, specific inhibitors etc; Targeting signaling pathways that increase sensitivity to conventional treatments; Molecular pathways targeted by environmental, physiological, or infectious agents. We will present these changes to our External Advisory Committee at our May 24, 2006 Symposium. The COBRE CCRD website can be found at www.RIH-COBRE-CARES.org. It lists NCRR funding for this Center.

该子项目是由NIH/NCRR资助的许多副标题之一。研究人员的构成新知识。癌症的主题g肿瘤的主题c;范围的变化并强调了对搜索的翻译潜力，我们的整体主题将立即� 癌症干预的分子靶一项更广泛的VASIC研究将鼓励研究人员在改进的诊断和治疗方法上，以进行分子的基础在2006年5月24日，COBRI CCRD网站上，对环境或感染力的敏感性。中心。