Research Training Program in Pulmonary Host Defense, Inflammation and Immunity

肺宿主防御、炎症和免疫研究培训项目

• 批准号: 7067770
• 负责人: Claire M Doerschuk
• 金额: $ 12.83万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7067770
• 关键词: Research; Training; Program; Pulmonary; Host

DESCRIPTION (provided by applicant): This new application seeks funding for a multi-disciplinary research training program in Pulmonary Host Defense, Inflammation and Immunity at Case Western Reserve University School of Medicine and Health for pre-doctoral Ph.D. or M.D./Ph.D. students engaged in thesis work and for medical students engaged in shortterm research training. Presently, the research programs of Case faculty and the training programs for postdoctoral fellows and junior faculty in pulmonary host defense and in immunobiology are strong, and many pre-doctoral graduate and medical students are interested in joining these programs. There is a clear need for enlarging this pulmonary host defense community to include these students who are at earlier stages of their career, both to excite them about pursuing research careers in lung disease and to provide them outstanding training opportunities in inflammation and immunity. The objectives of this research training program are to 1) include these young students in this community, 2) provide outstanding multi-disciplinary research training and a rigorous background in pulmonary physiology in health and disease, 3) facilitate interactions that apply newly emerging information about basic mechanisms of inflammation and immunity to pulmonary disease, 4) develop new effective mentoring programs, and 5) provide an infrastructure. Our goals are to provide outstanding collaborative multidisciplinary research training to prepare our trainees for successful careers in pulmonary host defense and immunobiology, to train research and physician scientists to translate findings freely between the basic and clinical spheres, and to provide excellent mentor- and co-mentorship, which itself is taught to our trainees and evaluated by them. Short-term training for medical students will provide them an opportunity to pursue an area of research in greater depth than is accomplished within the traditional curriculum and increase awareness of opportunities in research through well structured, mentored research experiences that lay the foundation for future involvement in research. The outstanding, highly interactive 36 program faculty are based in 13 departments and have primary interests in four areas: lung immunobiology, tuberculosis, mechanisms of inflammation and innate immunity, or mucosal immunity. Thus, students will have opportunities through co-mentorship to learn about forefront advances in basic mechanisms in inflammation and immunity and to apply these to address important questions in lung biology. Underrepresented minorities are specifically recruited to join this program. Our evaluation system allows us to continuously improve our training program, and our database tracks the careers of these trainees. (End of Abstract)

描述（由申请人提供）： 这项新申请为凯斯西储大学医学与健康学院的肺宿主防御、炎症和免疫学博士前博士生多学科研究培训项目寻求资金。或医学博士/博士学生从事论文工作以及为医学生从事短期研究培训。目前，凯斯学院的研究项目以及肺宿主防御和免疫生物学方面的博士后和初级教师培训项目实力雄厚，许多博士前研究生和医学生有兴趣加入这些项目。显然需要扩大这个肺部宿主防御社区，将这些处于职业生涯早期阶段的学生包括在内，既可以激发他们从事肺部疾病的研究事业，又可以为他们提供炎症和免疫方面出色的培训机会。该研究培训计划的目标是 1) 将这些年轻学生纳入该社区，2) 提供出色的多学科研究培训以及健康和疾病方面肺生理学的严格背景，3) 促进应用新兴信息的互动炎症和肺部疾病免疫的基本机制，4）制定新的有效指导计划，5）提供基础设施。我们的目标是提供出色的协作性多学科研究培训，使我们的学员为肺宿主防御和免疫生物学领域的成功职业做好准备，培训研究和医师科学家在基础和临床领域之间自由地转化研究结果，并提供优秀的导师和合作伙伴指导，它本身是教给我们的学员并由他们评估的。医学生的短期培训将为他们提供比传统课程更深入的研究领域的机会，并通过结构良好、受指导的研究经验提高对研究机会的认识，为未来参与医学研究奠定基础。研究。杰出、高度互动的 36 个项目教师分布在 13 个系，主要兴趣在四个领域：肺免疫生物学、结核病、炎症和先天免疫机制或粘膜免疫。因此，学生将有机会通过共同指导来了解炎症和免疫基本机制的前沿进展，并将其应用于解决肺部生物学的重要问题。代表性不足的少数族裔被专门招募来加入该计划。我们的评估系统使我们能够不断改进我们的培训计划，我们的数据库跟踪这些学员的职业生涯。 （摘要完）