BIOCHEMICAL, MORPHOLOGICAL, AND TRACE ELEMENT STUDIES IN ALZHEIMER'S DISESAE

阿尔茨海默病的生物化学、形态学和微量元素研究

• 批准号: 7379028
• 负责人: WILLIAM R MARKESBERY
• 金额: $ 13.12万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7379028
• 关键词: BIOCHEMICAL; MORPHOLOGICAL; TRACE; ELEMENT; STUDIES

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of the Alzheimer's Disease Research Center Clinical Core is to provide clinical data, study participants and the means of obtaining autopsy materials for research. It is designed to aid research on current central scientific questions in AD and related diseases. The clinical core does not address these questions directly, but makes available a group of well-characterized subjects to enable substantive research on these important current questions. To do this, the clinical core 1) follows a group of community-dwelling normal elderly individuals to autopsy, 2) follows an existing group of individuals with dementia to autopsy, 3) evaluates and diagnoses individuals with memory disorders, and 4) adds to the registry of individuals who are potential participants in research studies.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。阿尔茨海默氏病研究中心临床核心的目的是提供临床数据，研究参与者以及获得尸检材料进行研究的手段。它旨在帮助研究广告和相关疾病中当前的中心科学问题。临床核心并未直接解决这些问题，而是使一组特征良好的受试者可以对这些重要的当前问题进行实质性研究。为此，临床核心1）跟随一群社区居住的正常老年人进行尸检，2）遵循现有的痴呆症患者进行尸检，3）评估和诊断记忆障碍的人，4）4）增加了潜在参与者研究研究人员的注册表。