Online Adaptation of HIV Risk-Reduction Interventions

艾滋病毒风险降低干预措施的在线调整

• 批准号: 7117677
• 负责人: ERIC G BENOTSCH
• 金额: $ 20.71万
• 依托单位: UNIVERSITY OF COLORADO DENVER/HSC DENVER
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7117677
• 关键词: AIDS education /prevention; HIV infections; Internet; clinical research; computer assisted instruction; disease /disorder proneness /risk; educational resource design /development; focus groups; health behavior; high risk behavior /lifestyle; human subject; interpersonal relations; telemedicine

DESCRIPTION (provided by applicant): This application, submitted in response to PAR-03-078, From Intervention Development to Services: Exploratory Research Grants (R34), seeks funding for a 3 year project to adapt and field test two commonly-used and efficacious community-level HIV prevention interventions, Integrated Outreach and the Popular Opinion Leader (POL) Model, for use in online environments such as "chat rooms." It is becoming increasingly common for high-risk individuals to meet sexual partners online. In multiple studies with diverse populations, researchers have documented that persons who seek sexual partners online show a pattern of increased sexual risk behaviors. The Internet also has potential utility to reach populations at risk for HIV. We believe that community-level interventions (Integrated Outreach, POL) which intervene with populations in their natural environment during their day-to-day interactions show particular promise for adaptation for online use. To examine this, we will conduct 3 phases of research: (1) initial interviews and focus groups with persons using chat rooms and with providers who conduct online interventions (2) using information obtained during the formative stage, we will develop treatment protocols and standardized intervention manuals building upon our preliminary conceptualization of these interventions as adapted for the Internet, (3) we will conduct pilot studies and a small-scale test-of-concept field test to examine the potential efficacy of the interventions to alter community norms, attitudes, and HIV risk behavior. The field test will use a randomized design with 4 chat sites randomly assigned to 1 of 3 conditions: (a) Integrated Outreach, (b) POL, and (c) assessment-only control. Consistent with the PA, methods used will provide preliminary data concerning the feasibility, acceptability, and practicality of online community-level interventions. The proposed methods will also permit us to collect data needed to provide initial evidence of efficacy needed for a larger-scale trial, including estimates of outcome parameters such as intervention effect sizes.

描述（由申请人提供）：本申请是为了响应 PAR-03-078“从干预开发到服务：探索性研究补助金 (R34)”而提交，寻求资助一个为期 3 年的项目，以适应和现场测试两种常用和有效的社区级艾滋病毒预防干预措施、综合外展和大众意见领袖（POL）模型，用于“聊天室”等在线环境。高风险人群在网上结识性伴侣的情况变得越来越普遍。在针对不同人群的多项研究中，研究人员记录了在网上寻找性伴侣的人表现​​出性风险行为增加的模式。互联网还具有接触艾滋病毒高危人群的潜在效用。我们相信，社区层面的干预措施（综合外展，POL）在自然环境中的人群日常互动中进行干预，这对于适应在线使用显示出特别的希望。为了检验这一点，我们将进行 3 个阶段的研究：(1) 与使用聊天室的人员以及进行在线干预的提供者进行初步访谈和焦点小组 (2) 使用在形成阶段获得的信息，我们将制定治疗方案并标准化干预手册建立在我们对这些干预措施的初步概念化之上，以适应互联网，(3)我们将进行试点研究和小规模概念测试现场测试，以检查干预措施改变社区规范、态度的潜在功效和艾滋病毒危险行为。现场测试将采用随机设计，将 4 个聊天站点随机分配到 3 个条件之一：(a) 综合外展、(b) POL 和 (c) 仅评估控制。与 PA 一致，所使用的方法将提供有关在线社区一级干预措施的可行性、可接受性和实用性的初步数据。所提出的方法还将使我们能够收集所需的数据，以提供更大规模试验所需的疗效的初步证据，包括对干预效果大小等结果参数的估计。