Nutrional Epidemiology of Cancer

癌症的营养流行病学

基本信息

批准号：
7283671
负责人：
Meir Stampfer
金额：
$ 49.5万
依托单位：
HARVARD SCHOOL OF PUBLIC HEALTH
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-09-01 至 2009-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7283671
关键词：
Academia Accounting Acids Address Administrator Adolescence Adult Advertisements Advertising Advisory Committees Affect African American Age at Menarche Alcohol consumption Alcohol dehydrogenase Alcohols Algorithms American American Public Health Association Analysis of Variance Animal Experiments Animals Annual Reports Apoptosis Appendix Applications Grants Appointment Architecture Area Arts Asia Asians Aspirin Attention Authorship Award Basic Science Behavior Behavioral Behavioral Sciences Benign Beta Carotene Biochemical Biochemical Genetics Biochemical Markers Biochemistry Biological Biological Assay Biological Markers Biology Biometry Blood specimen Body mass index Boston Brazil Breast Breast Cancer Epidemiology Breast Cancer Prevention Budgets CCR Calcium Canada Cancer Biology Cancer Burden Cancer Center Cancer Control Cancer Etiology Cancer Hospital Cancer Patient Cancer and Nutrition Carbohydrate Biochemistry Carcinogen Metabolism Carcinogens Cardiovascular Diseases Cardiovascular system Carotenoids Case Study Case-Control Studies Categories Causations Cell Communication Cell Cycle Checkpoint Cell Cycle Regulation Cell Death Cell physiology Cells Cellular biology Cereals Characteristics Chemicals Chemoprevention Child Childhood China Chromatin Structure Chromosome Mapping Class Climate Clinical Clinical Nutrition Clinical Oncology Clinical Research Clinical Trials Clinical effectiveness Code Cohort Studies Collaborations Collection Colon Colon Carcinoma Commit Communicable Diseases Communication Communities Community Health Community Medicine Competence Complement Complex Computer software Condition Conflict of Interest Consultations Controlled Study Coronary heart disease Counseling Country Creativeness Critiques Cytidine Monophosphate DNA DNA Damage DNA Repair DNA Structure DNA biosynthesis DNA chemical synthesis Daily Dairy Products Dana-Farber Cancer Institute Data Data Analyses Data Set Data Sources Databases Depth Development Development Plans Diabetes Mellitus Diagnosis Diet Diet Records Dietary Assessment Dietary Component Dietary Factors Dietary intake Discipline Disclosure Discrimination Disease Division of Cancer Prevention Doctor of Philosophy Doctor of Public Health Early Diagnosis Education Educational Curriculum Educational process of instructing Educational workshop Electrolytes Elements Employee Strikes End Point Endocrine system Energy Intake Enrollment Ensure Environment Environmental Epidemiology Environmental Exposure Environmental Risk Factor Enzyme Kinetics Enzymes Epidemiologic Methods Epidemiologic Studies Epidemiologist Epidemiology Epidemiology, Other Epithelium Equilibrium Erythrocytes Estrogens Ethical Issues Ethics Ethnic group Etiology Europe Evaluation Evolution Exclusion Exercise Facility Construction Funding Category Faculty Failure Familiarity Family Fatty acid glycerol esters Feedback Fellowship Fertilization Fiber Financial Support Finland Folate Folic Acid Follow-Up Studies Food Food Interactions Fostering Foundations Frequencies Funding Future Gender General Hospitals Generations Genes Genetic Genetic Markers Genetic Polymorphism Genetic Predisposition to Disease Genetic Transcription Genetic Translation Genome Genome Stability Genotype Genus Cola Germ Lines Goals Government Grant Grant Review Grant Review Process Greece Growth Guidelines Hand Head Health Health Occupations Health Personnel Health Professional Heart Diseases Height Hispanics Histopathology Historically Black Colleges and Universities Home environment Hormonal Hormones Hospitals Housing Human Human Resources Hyperinsulinism Hypertension Immune response Incidence India Individual Infant Infection Infectious Agent Informed Consent Institutes Institution Institutional National Research Service Award Insulin Insulin Resistance Intake Interdisciplinary Study Intermediate Variables International Intervention Investigation Isoflavones Japan Joints Journal of the National Cancer Institute Journals K-Series Research Career Programs Knowledge Korea Laboratories Lead Leadership Learning Length Lesion Letters Life Life Style Light Lignans Link Liquid substance Literature Logistic Regressions Longevity Lung Mails Malignant - descriptor Malignant Neoplasms Malignant neoplasm of kidney Malignant neoplasm of ovary Malignant neoplasm of pancreas Malignant neoplasm of prostate Malignant neoplasm of urinary bladder Mammary Neoplasms Mammographic Density Manuscripts Massachusetts Master&apos s Degree Measurement Measures Meat Mediating Medical Medical Students Medicine Mentors Mentorship Meta-Analysis Metabolic Control Metabolism Methodology Methods Methylenetetrahydrofolate reductase (NADPH)Mexico Micronutrients Minerals Minor Minority Modeling Modems Modification Molecular Molecular Biology Molecular Epidemiology Molecular Epidemiology of Cancer Molecular Genetics Molecular Motors Monitor Monograph Morphology Mothers Motor Multivariate Analysis Mutagenesis Mutagenicity Tests Mutagens Myocardial Ischemia NCI Advisory Board or Group National Cancer Institute Natural History Nature Neoplasm Metastasis Netherlands Numbers Nurses&apos Health Study Nursing Schools Nutrient Nutritional Nutritional Biochemistry Nutritional Study Nutritional status Nuts Obesity Observational Study Occupational Health Occupations Oncologist Oral Oral Examination Other Minority Other Resources Outcome Ovary Oxidation-Reduction Oxidoreductase PSA screening Pamphlets Pancreas Paper Participant Pathology Pathway interactions Pattern Persons Pharmaceutical Preparations Phase Phenotype Physical activity Physicians Physiology Phytochemical Phytoestrogens Pilot Projects Placement Plasma Play Pliability Policies Population Population Sciences Positioning Attribute Post-Translational Regulation Postdoctoral Fellow Predisposition Pregnancy Preparation Prevention Prevention program Preventive Preventive Medicine Primary Prevention Principal Investigator Probability Problem Solving Procedures Process Productivity Professional Organizations Program Effectiveness Program Evaluation Program Reviews Property Prospective Studies Proteins Public Health Public Health Practice Public Health Schools Publications Published Comment Publishing Purpose Qualifying Questionnaires RNA Race Randomized Clinical Trials Randomized Controlled Clinical Trials Range Rate Reading Recommendation Recruitment Activity Regression Analysis Regulation Renal carcinoma Reporting Reproduction spores Research Research Activity Research Design Research Ethics Research Infrastructure Research Methodology Research Personnel Research Project Grants Research Proposals Research Support Research Training Resources Review Committee Risk Risk Assessment Risk Factors Risk Marker Role Sampling Schedule Schools Science Scientist Score Screening procedure Seeds Selection Bias Selenium Series Serologic tests Services Signal Transduction Site Site Visit Smoke Social Behavior Social Policies Social Sciences Societies Solid Somatomedins Source Specialist Specific qualifier value Specimen Staging Standards of Weights and Measures Statistical Methods Stress Structural Models Structure Structure of nail of toe Students Study Section Study of serum Supervision Surveys Susceptibility Gene Sweden System Tanzania Techniques Technology Testing Textbooks Time Tissue Microarray Toxicogenetics Trace Elements Training Training Activity Training Programs Training Support Training and Infrastructure Transcript Translating Translation Process Underrepresented Minority United States National Academy of Sciences United States National Institutes of Health Universities Update Urban Hospitals Ursidae Family Uterus Validation Variant Viral Vision Visit Vitamin D Vitamin D3 Receptor Vitamin E Vitamins Wages Weight Weight Gain Woman Women&apos s Health Work Workplace Writing Zinc aged anticancer research base behavior change breast cancer diagnosis bullying cancer cell cancer education cancer epidemiology cancer prevention cancer risk cancer site cancer therapy carcinogenesis career case control cell motility cell transformation clinical epidemiology cohort college concept critical developmental period day design desire diet and cancer disease natural history disorder control epidemiology study ethnic minority population experience falls feeding field study folic acid metabolism follow-up food science fruits and vegetables gene environment interaction gene interaction genetic epidemiology health training high school human disease improved in utero innovation insight interdisciplinary approach interest knowledge base lecturer lectures lomustine/methotrexate/procarbazine protocol lycopene malignant breast neoplasm mathematical model medical schools medically underserved member men method development mortality multidisciplinary novel novel strategies nutrition nutritional epidemiology oncology oral communication outcome forecast planetary Atmosphere post-doctoral training pre-doctoral prevent professor programs prospective quality assurance racial and ethnic receptor repaired repository research and development research study respiratory response scientific organization skills social software systems sound success symposium teacher tobacco control tool treatment program trend tumor tumor progression validation studies willingness

项目摘要

DESCRIPTION (provided by applicant): This education program is being submitted with the encouragement and advice of the NCI Training Branch. Advancing nutrition research through expanded education and training programs, especially those related to nutrition and cancer, is a high priority of the Nutritional Science Research Group of the Division of Cancer Prevention at the National Cancer Institute. This application meets the guidelines for the R25T mechanism, including the provision of sustained leadership, dedicated faculty time, a well-defined specialized curriculum, interdisciplinary research environments, and more than one mentor per program participant. This mechanism is particularly appropriate because it is adaptable to the special interdisciplinary, yet focused, needs of this program, which is based on the interface of nutrition and epidemiology. This program is led by Dr. Meir Stampfer, with Dr. Walter Willett as co-Principal Investigator and Dr. Edward Giovannucci as Education Director. The proposed program has a wealth of other resources upon which to draw. The Department of Epidemiology at Harvard School of Public Health has long been a recognized center for didactic training in epidemiologic methods and cancer epidemiology in general. The Department of Nutrition has focused considerable energy in nutritional epidemiology. This educational program also draws on diverse research opportunities within the Dana-Farber/Harvard Cancer Center (DF/HCC), a matrix cancer center representing cancer research across seven Harvard-affiliated institutions. This work has included major developments in the area of diet and cancer such as the creation of three large cohorts comprising over 250,000 men and women with repeated measures of diet followed for as long as 25 years. Participants in this program will also have the opportunity to gain familiarity with other aspects of the broad areas of epidemiology and cancer etiology and prevention that extend beyond the focus of the training grant. Through the proposed training grant, we plan to bring together the various elements already in place, and create new elements to build a coherent and focused interdisciplinary program in nutritional epidemiology of cancer. The proposed training grant in Nutritional Epidemiology of Cancer will provide a unique niche, and it will be complementary, and synergistic, with the other training grants to foster a strong environment for cancer prevention and control, based on sound biology.

描述（由申请人提供）：本教育计划是在 NCI 培训部门的鼓励和建议下提交的。通过扩大教育和培训计划，特别是与营养和癌症相关的教育和培训计划，推进营养研究，是国家癌症研究所癌症预防司营养科学研究小组的首要任务。该应用程序符合 R25T 机制的指导方针，包括提供持续的领导、敬业的教员时间、明确的专业课程、跨学科研究环境以及每个项目参与者多名导师。这种机制特别合适，因为它能够适应该计划的特殊跨学科但重点突出的需求，该计划基于营养学和流行病学的结合。该项目由 Meir Stampfer 博士领导，Walter Willett 博士担任联合首席研究员，Edward Giovannucci 博士担任教育总监。拟议的计划还有大量其他资源可供利用。哈佛大学公共卫生学院流行病学系长期以来一直是公认的流行病学方法和癌症流行病学教学培训中心。营养系在营养流行病学方面投入了大量精力。该教育计划还利用了丹娜—法伯癌症研究所/哈佛大学癌症中心 (DF/HCC) 内的各种研究机会，该中心是一个矩阵癌症中心，代表七个哈佛大学附属机构的癌症研究。这项工作包括饮食和癌症领域的重大进展，例如创建了由超过 250,000 名男性和女性组成的三个大型队列，并对其进行长达 25 年的重复饮食测量。该计划的参与者还将有机会熟悉流行病学、癌症病因学和预防等广泛领域的其他方面，这些方面超出了培训补助金的重点。通过拟议的培训拨款，我们计划整合现有的各种要素，并创造新的要素，以建立一个连贯且有针对性的癌症营养流行病学跨学科项目。拟议的癌症营养流行病学培训补助金将提供一个独特的利基，并将与其他培训补助金相补充和协同，以在健全的生物学基础上为癌症预防和控制营造一个强有力的环境。