Continuous BP monitor for dialysis applications

用于透析应用的连续血压监测仪

基本信息

批准号：
7271794
负责人：
MARTIN Carl BARUCH
金额：
$ 9.96万
依托单位：
EMPIRICAL TECHNOLOGIES CORPORATION
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-06-04 至 2008-06-03
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7271794
关键词：
Address Affect Algorithms American Area Arrhythmia Arterial Lines Arteries Atrial Fibrillation Australia Back Blood Pressure Blood Pressure Monitors Blood flow Braces-Orthopedic appliances Breast Caliber Calibration Cardiac Cardiovascular Diseases Cardiovascular system Carotid Arteries Catheters Central Artery Cessation of life Characteristics Chronic Kidney Failure Class Clinical Research Colon Carcinoma Complex Condition Consent Coronary Angiography Coupled Couples Coupling Data Databases Descending aorta Development Device Designs Devices Diabetes Mellitus Dialysis patients Dialysis procedure Diastolic blood pressure Differential Mortality Distant Effectiveness Elevation End stage renal failure England Epidemiologic Studies Europe Excess Mortality Fistula Forearm Forehead General Population Gold Growth Hand Head Health Heart Heart Diseases Heart Rate Height Hemodialysis Hypertension Immunosuppression Individual Invasive Kidney Kidney Failure Kidney Transplantation Knowledge Lateral Light Masks Mattresses Measurement Measures Medical center Miniaturization Modeling Monitor Morphologic artifacts Movement Nephrology Noise North America Numbers Operative Surgical Procedures Organ Palpation Patient Monitoring Patients Performance Peripheral Phase Physical Dialysis Physiologic pulse Population Positioning Attribute Preparation Prevention strategy Procedures Process Prostate Protocols documentation Public Health Publishing Pulse Pressure Pulse taking Radial Randomized Controlled Trials Range Rate Reading Relative (related person)Renal function Research Risk Running Shapes Signal Transduction Site Staging Standards of Weights and Measures Stream Symptoms System Target Populations Techniques Technology Testing Therapeutic immunosuppression Thoracic aorta Time Toxic effect Transplant Recipients Travel United States Food and Drug Administration Universities Upper arm Validation Variant Virginia Wales Wireless Technology Work Wrist abdominal aorta aged base blood pressure regulation data acquisition data modeling design diabetic electric impedance improved instrument meter miniaturize neonate normotensive novel outcome forecast physical model pressure programs prototype radial artery renal artery research study response sensor size telemetering transmission process trend

项目摘要

DESCRIPTION (provided by applicant): The need for the continuous monitoring of blood pressure in patients undergoing dialysis is steadily increasing. While the population undergoing dialysis, presently at about 400k in the US, is growing along with the global growth in chronic kidney disease (CKD) patients, the general health of the dialysis population is declining as increasingly sicker patients undergo the very invasive procedure. In response ETC proposes to develop and test a wireless wrist-worn continuous blood pressure monitor that will permit the centralized monitoring of patients undergoing dialysis. The device is non-occlusive and utilizes a novel physical model of the radial pulse to determine BP via pulse analysis. The compact design of the device makes patient mobility and wireless connectivity possible. The device's effectiveness in comparison to gold standards will be tested in a clinical study involving 95 normotensive subjects as well as dialysis and kidney transplant patients.

描述（由申请人提供）：对接受透析的患者进行持续血压监测的需求正在稳步增加。尽管目前美国接受透析的人数约为 40 万，并且随着全球慢性肾病 (CKD) 患者的增长而不断增长，但随着病情越来越严重的患者接受这种侵入性很强的手术，透析人群的总体健康状况正在下降。为此，ETC 提议开发和测试无线腕戴式连续血压监测仪，以便对接受透析的患者进行集中监测。该设备是非闭塞性的，利用径向脉冲的新颖物理模型通过脉冲分析来确定血压。该设备的紧凑设计使患者移动和无线连接成为可能。该设备与金标准相比的有效性将在一项涉及 95 名血压正常受试者以及透析和肾移植患者的临床研究中进行测试。