Research Priorities in Ambulatory Management of Obstructive Sleep Apnea Workshop

阻塞性睡眠呼吸暂停门诊管理研讨会的研究重点

基本信息

批准号：
7413515
负责人：
SAMUEL T. KUNA
金额：
$ 4.65万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-09-30 至 2008-09-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7413515
关键词：
Research Priorities Ambulatory Management Obstructive

项目摘要

The application seeks partial financial support for a workshop on research priorities in the ambulatory management of obstructive sleep apnea (OSA) to be held on October 15-16, 2007 in Washington, DC. Moderate to severe OSA is estimated to affect 4% of adult females and 9% of adult males in the US and a large majority of these individuals are undiagnosed. A large body of data now supports that OSA is an independent risk factor for motor vehicle accidents, neurocognitive deficits, and cardiovascular morbidity and mortality. Substantial evidence also supports that appropriate treatment of OSA reduces the risk of these consequences. However there is a major problem with patient access to diagnosis and treatment of OSA based on the need to perform costly and labor-intensive polysomnography in a sleep laboratory. Technological improvements may allow for the use of simplified portable monitor testing for OSA in diverse settings, including unattended home recordings. Such an approach might reduce cost and increase patient access to testing, leading to earlier recognition of disease and faster initiation of treatment, thereby reducing the health care burden associated with OSA. Interest in the clinical application of portable monitor devices is growing rapidly, and in some contexts, portable monitoring has become a mainstay approach to the management of OSA. Despite the intuitive appeal of portable monitor testing, validation data remain limited. A recent report from the Institute of Medicine and evidence based reviews from AHRQ and professional societies find major deficiencies particularly with regard to unattended home portable monitor testing. The planned workshop on research priorities in ambulatory management of OSA is a direct response to these reports. The workshop will bring together diverse stakeholders with interest in portable monitor testing to establish the research priorities regarding portable monitor testing and develop specific recommendations regarding methodological issues in this critical area. We submit that this workshop is an essential ?next step? to ensuring that there is substantive advancement of scientific knowledge in this important field.

该申请寻求部分财政支持，以进行有关研究优先事项的研讨会梗阻性睡眠呼吸暂停（OSA）将于2007年10月15日至16日举行在华盛顿特区。估计中度至重度OSA会影响4％的成年女性，而9％在美国和大多数这些人的成年男性中，未被诊断。一个大现在，数据机构支持OSA是机动车事故的独立风险因素，神经认知缺陷，心血管发病率和死亡率。也有大量证据支持对OSA进行适当治疗的支持可以降低这些后果的风险。然而患者根据患者获得诊断和治疗OSA的主要问题需要在睡眠实验室中执行昂贵且劳动密集型的多聚会学。技术改进可能允许使用简化的便携式监视器测试 OSA在不同的环境中，包括无人看管的房屋录音。这样的方法可能降低成本并增加患者接受测试，从而较早认识到疾病和更快地开始治疗，从而减轻与OSA相关的医疗保健负担。对便携式监视器设备的临床应用的兴趣正在迅速增长，在某些方面上下文，便携式监控已成为OSA管理的主要方法。尽管便携式监视器测试具有直观的吸引力，但验证数据仍然有限。最近医学研究所的报告和证据基于AHRQ和专业的评论社会发现主要缺陷，尤其测试。 OSA门诊管理研究重点的计划工作室是一个对这些报告的直接响应。研讨会将使各种利益相关者与对便携式监视器测试的兴趣，以建立有关便携式监视器的研究优先级在这个关键的方法中测试并制定有关方法论问题区域。我们认为这个研讨会是必不可少的？下一步？确保有在这个重要领域的科学知识的实质性进步。