System for the Stanford Microarray Database

斯坦福微阵列数据库系统

• 批准号: 6731823
• 负责人: Gavin J Sherlock
• 金额: $ 44.06万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2005-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6731823
• 关键词: bioinformatics; biomedical equipment purchase; computer system hardware; information dissemination; microarray technology; molecular biology information system

DESCRIPTION (provided by applicant): The Stanford Microarray Database stores microarray data and associated biological annotation, and provides interfaces for retrieval, quality assessment and analysis of those data. SMD currently hosts the data of a broad community of investigators who study a diverse set of biological and medical questions. Many of these investigators funded by the NIH, although few of them have funding for the bioinformatics and computational support that SMD provides. This application seeks funding to purchase a new computer system for the Stanford Microarray Database, which will replace the current system, which is nearly three years old and is inadequate to meet the increasing demands of SMD users. Specifically, this grant proposal seeks funding for a server to accommodate the database, a server to provide additional computational power, a RAID array for data storage, three RAIDs for image storage and backup, a backup library, a partitioning license from Oracle, and the appropriate uninterruptable power supplies and storage racks for the machines. SMD has strong institutional support, and support for staff is provided by funding for microarray studies of human cancer in the joint laboratory of Dr. David Botstein and Dr. Patrick Brown. However there exists no SMD funding for purchase of this new system. Specifically, the new system that we are seeking to purchase will provide long-term expandability, increased processing power for more computationally intensive analyses, increased performance of data retrieval, a better development and testing environment and a decrease in downtime due to scheduled data backups. Without this new system SMD will be unable to meet the growing demands of its community of researchers.

描述（由申请人提供）： 斯坦福微阵列数据库存储微阵列数据和相关的生物注释，并提供用于检索、质量评估和分析这些数据的接口。 SMD 目前托管着广泛的研究人员群体的数据，这些研究人员研究各种生物学和医学问题。这些研究人员中的许多人都得到了 NIH 的资助，尽管他们中很少有人有资金支持 SMD 提供的生物信息学和计算支持。 该申请寻求资金为斯坦福微阵列数据库购买一套新的计算机系统，该系统将取代当前的系统，该系统已经使用了近三年，不足以满足 SMD 用户日益增长的需求。具体来说，该拨款提案寻求资金用于容纳数据库的服务器、提供额外计算能力的服务器、用于数据存储的 RAID 阵列、用于图像存储和备份的三个 RAID、一个备份库、Oracle 的分区许可证以及适合机器的不间断电源和存储架。 SMD 拥有强大的机构支持，并通过资助 David Botstein 博士和 Patrick Brown 博士联合实验室的人类癌症微阵列研究来为工作人员提供支持。然而，SMD 没有资金用于购买这个新系统。具体来说，我们寻求购买的新系统将提供长期可扩展性、增强的处理能力以进行更多计算密集型分析、提高数据检索性能、更好的开发和测试环境以及减少由于计划数据备份而导致的停机时间。如果没有这个新系统，SMD 将无法满足其研究人员群体日益增长的需求。