Latin America Workshop On Denge

拉丁美洲登格研讨会

• 批准号: 7750458
• 负责人: Jorge E Osorio
• 金额: $ 1.2万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7750458
• 关键词: American; Americas; Animal Model; Antiviral Agents; Appearance; Area; Arthropods; Cessation of life; Clinical Management; Clinical Trials; Colombia; Country; Dengue; Dengue Hemorrhagic Fever; Dengue Shock Syndrome; Dengue Virus; Detection; Developed Countries; Developing Countries; Development; Diagnosis; Diagnostic; Disease; Educational workshop; Epidemiology; Family; Fever; Flaviviridae; Funding Opportunities; Geographic Locations; Goals; Government; Hand; Health; Hearing; Human; Institution; International; Knowledge; Laboratories; Latin America; Learning; Licensing; Methods; Molecular; Molecular Diagnostic Techniques; Participant; Pathogenesis; Pharmaceutical Preparations; Population Growth; Prevention; Public Health; Regulation; Research; Running; Science; Serologic tests; Serotyping; Site; Social Change; Techniques; Testing; Training; Travel; Tropical Disease; Update; Urbanization; Vaccines; Virus; Virus Diseases; Work; authority; bone; graduate student; improved; lecturer; lectures; multidisciplinary; skills; therapeutic vaccine; transmission process; vaccine development; vector control

DESCRIPTION (provided by applicant): Dengue viruses (DENV) include four serotypes (DENV-1 - DENV-4) that belong to the Flaviviridae family and cause the most important arthropod-borne viral infection of humans with about 100 million cases and 25,000 deaths annually. DENV causes classic Dengue ("break-bone") fever (DF), and more severe and sometimes fatal dengue hemorrhagic fever (DHF)/dengue shock syndrome (DSS). In tropical and subtropical regions in the Americas, DF and DHF is considered one of the most serious health problems; moreover the demographic changes, the rapid urbanization and the travels around the world, has promoted the appearance of the disease in new geographic regions. In some Latin America countries, all four DENV serotypes are actively circulating. In the past 20 years, rapid epidemiological changes have manifested as a result of continuous population growth, uncontrolled and unplanned urbanization, increased intercountry travel and other social changes. All of these have created ideal conditions for increased transmission of multiple dengue virus serotypes in most of the tropical countries of the world. With this workshop, our goal is to provide an update of important multidisciplinary aspects of the Dengue, including: pathogenesis, prevention, control, treatment and diagnosis. In addition, in laboratory sessions, participants will learn important and improved techniques used for dengue diagnosis. Moreover, this workshop will provide an opportunity for scientific exchange between international institutions in developed countries and academic and regulatory authorities in Latin America.

描述（由申请人提供）：登革热病毒 (DENV) 包括四种血清型 (DENV-1 - DENV-4)，属于黄病毒科，引起人类最重要的节肢动物传播病毒感染，造成约 1 亿病例和 25,000 人死亡每年。 DENV 会引起典型的登革热（“断骨”）热 (DF)，以及更严重且有时致命的登革出血热 (DHF)/登革休克综合征 (DSS)。在美洲热带和亚热带地区，DF和DHF被认为是最严重的健康问题之一；此外，人口变化、快速城市化和世界各地的旅行，促进了该疾病在新地理区域的出现。在一些拉丁美洲国家，所有四种 DENV 血清型都在活跃传播。过去20年来，人口持续增长、不受控制和无计划的城市化、跨国旅行增加和其他社会变化导致流行病学发生快速变化。所有这些都为世界上大多数热带国家增加多种登革热病毒血清型的传播创造了理想的条件。通过这次研讨会，我们的目标是提供登革热重要的多学科方面的最新信息，包括：发病机制、预防、控制、治疗和诊断。此外，在实验室课程中，参与者将学习用于登革热诊断的重要且改进的技术。此外，本次研讨会将为发达国家的国际机构与拉丁美洲的学术和监管机构之间的科学交流提供机会。