Enterprise Storage In A Collaborative Neuroimaging Environment

协作神经影像环境中的企业存储

• 批准号: 7209718
• 负责人: Hans Joseph Johnson
• 金额: $ 40.45万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7209718
• 关键词: Address; Advanced Development; Biological Preservation; Collaborations; Communities; Data; Data Analyses; Data Collection; Data Set; Databases; Development; Disease; Ensure; Environment; Extramural Activities; Financial Support; Funding; Guidelines; Health Care Costs; Heterogeneity; Image; Incidence; Information Resources; Institution; Iowa; Libraries; Modeling; Mood Disorders; Nature; Numbers; Ownership; Performance; Public Health; Recording of previous events; Research; Research Ethics Committees; Research Personnel; Resources; Schizophrenia; Science; Services; Site; Solutions; Standards of Weights and Measures; System; Universities; addiction; base; cost; cost effective; data management; endophenotype; improved; neuroimaging; novel; novel diagnostics; relating to nervous system; repository; skills; success; virtual

DESCRIPTION (provided by applicant): The proposed Enterprise Storage Solution (ESS), comprising of a Hewlett Packard Enterprise Virtual Array with EFS Clustered Gateway and EML Tape Library, will allow the Iowa Neuroimaging Center (INC) to provide high quality, high performance data management and storage for a large number of projects. It is difficult to assess the storage requirements for the data collection and analysis necessary to perform the science of neuroimaging. When the institutional guidelines and conformance requirements of that scientific data are considered, the task becomes even more daunting. The ESS will enable the INC to globally manage data, ensure scientific research continuance, satisfy regulatory and compliance standards, and improve resource utilization. The ESS will minimize total cost of ownership and reduce management complexity by addressing all aspects of INC storage needs in single unified system. The Iowa Neuroimaging Center (INC) realizes that providing low cost and reliable storage services are imperative to ensure continued success in the pioneering research that is performed at The University of Iowa. To maximize the scientific impact of each collected data set the INC adheres to stringent data-sharing standards and provides a long-term data retention model for the aggregation and preservation of knowledge resources. The ability to rely on the proposed ESS and the associated competitive storage costs will allow submission of strong proposals for gaining continued financial support through intramural and extramural funding. The neuroimaging community at The University of Iowa has a long history of producing exceptional science. The INC recognizes that collaborations between a diverse group of investigators, reflecting a variety of academic backgrounds and skills, will be more competitive and better equipped to succeed. The ESS is necessary for supporting multi-site studies that generate very large amounts of data due to their collaborative nature. The ability to share and combine data from multiple research institutions is critical to uncovering the separable endophenotypes that contribute to the heterogeneity of many disorders studied by INC investigators. Relevance The funded projects that will benefit from the IRB imaging data repository explore the neural basis of schizophrenia, affective disorder, addiction, and other disorders that have a high incidence, and that pose a huge public health cost burden. The proposed repository is extremely cost effective in that it will make existing data analyses much more efficient, and will also permit the development of new, novel analysis strategies that could significantly advance the development of new diagnostic and treatment approaches.

描述（由申请人提供）：拟议的企业存储解决方案 (ESS) 由具有 EFS 集群网关和 EML 磁带库的 Hewlett Packard Enterprise 虚拟阵列组成，将使爱荷华州神经影像中心 (INC) 能够提供高质量、高性能的数据大量项目的管理和存储。评估执行神经影像科学所需的数据收集和分析的存储要求是很困难的。当考虑到科学数据的机构指南和一致性要求时，这项任务变得更加艰巨。 ESS 将使 INC 能够在全球范围内管理数据，确保科学研究的连续性，满足监管和合规标准，并提高资源利用率。 ESS 通过在单个统一系统中满足 INC 存储需求的各个方面，将最大限度地降低总拥有成本并降低管理复杂性。爱荷华州神经影像中心 (INC) 意识到，提供低成本和可靠的存储服务对于确保爱荷华大学开展的开创性研究持续取得成功至关重要。为了最大限度地发挥每个收集数据集的科学影响，INC 遵守严格的数据共享标准，并为知识资源的聚合和保存提供长期数据保留模型。依靠拟议的 ESS 和相关的有竞争力的存储成本的能力将允许提交强有力的提案，通过校内和校外资金获得持续的财政支持。爱荷华大学的神经影像学界在创造卓越科学方面有着悠久的历史。 INC 认识到，反映不同学术背景和技能的多元化研究人员群体之间的合作将更具竞争力，也更有能力取得成功。 ESS 对于支持多站点研究是必要的，这些研究由于其协作性质而生成大量数据。共享和合并来自多个研究机构的数据的能力对于揭示可分离的内表型至关重要，这些内表型导致 INC 研究人员研究的许多疾病的异质性。相关性 受益于 IRB 成像数据存储库的资助项目探索精神分裂症、情感障碍、成瘾和其他发病率高且造成巨大公共卫生成本负担的疾病的神经基础。拟议的存储库极具成本效益，因为它将使现有数据分析更加有效，并且还允许开发新的、新颖的分析策略，从而显着推进新诊断和治疗方法的开发。

项目成果

Early atrophy of pallidum and accumbens nucleus in Huntington's disease.

• DOI: 10.1007/s00415-010-5768-0
• 发表时间: 2011-03
• 期刊: Journal of neurology
• 影响因子: 6
• 作者: van den Bogaard SJ;Dumas EM;Acharya TP;Johnson H;Langbehn DR;Scahill RI;Tabrizi SJ;van Buchem MA;van der Grond J;Roos RA;TRACK-HD Investigator Group
• 通讯作者: TRACK-HD Investigator Group