CORE--ANIMAL

核心--动物

• 批准号: 6728400
• 负责人: KAREN A. FAGAN
• 金额: $ 8.09万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6728400
• 关键词: animal colony; biomedical facility; cow; hyperbaric chamber; laboratory mouse; laboratory rat; pulmonary circulation

DESCRIPTION (provided by applicant): Function: This core provides a range of services that are essential to the success of the overall program: * In vivo studies of pulmonary and systematic circulation. * Operation of hypo- and hyperbaric chambers. * Coordination of management of animals in large animal hypobaric chambers at Colorado State University in Fort Collins, CO. * Maintenance of breeding colonies for inbred mice. * Preparation and renewal of animal Services. Provided: In vivo studies of pulmonary and systematic circulation: The Animal Core provides a vital bridge linking in vitro studies in isolated organs and vessels and cultured cells to the in vivo setting. This permits the important test of relevance of concepts developed in reduced preparations to intact animals.

描述（由申请人提供）： 功能：该核心提供一系列对于整体成功至关重要的服务 项目： * 肺循环和体循环的体内研究。 * 低压舱和高压舱的操作。 * 协调科罗拉多州柯林斯堡科罗拉多州立大学大型动物低压室中的动物管理。 * 维护近交小鼠的繁殖群。 * 动物服务的准备和更新。 提供：肺循环和体循环的体内研究：动物核心提供了连接的重要桥梁 离体器官和血管以及培养细胞到体内环境的体外研究。这允许对在减少的准备中开发的概念与完整动物的相关性进行重要测试。