Vascular Depression and Function in Older Latinos

老年拉丁裔的血管抑郁和功能

• 批准号: 6875670
• 负责人: Hector M Gonzalez
• 金额: $ 6.95万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-01 至 2005-12-04
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6875670
• 关键词: Mexican Americans; behavioral /social science research tag; cerebrovascular disorders; clinical research; cognition disorders; depression; diabetes mellitus; disease /disorder proneness /risk; health care service availability; human subject; hypertension; longitudinal human study

DESCRIPTION (provided by applicant): Elevated depressive symptoms affect nearly 26 percent of older Mexican Americans, but very few (9.1 percent) receive treatment. Older Mexican Americans have high rates of diabetes (33 percent), hypertension (62 percent) and depressive symptoms, which are risks associated with cerebrovascular disease. High rates of cerebrovascular disease risks and low stroke prevention awareness among Latinos presents a looming public health problem as this large population continues to rapidly grow. Currently little is known about the course and progression of mostly untreated depression, particularly as it relates to cerebrovascular disease in this large and rapidly growing population. The overall goal of the proposed research plan is to develop and refine methods for a longitudinal, population-based study of depression and cerebrovascular disease and their association with cognitive and functional status of older Mexican Americans. The Sacramento Area Latino Study on Aging (SALSA) is a population-based, longitudinal cohort study of 1,789 older Latinos of primarily Mexican descent. SALSA has a representative sample, which makes it an especially valuable data source for studying the predictors of cognitive and functional impairment and decline that are associated with depression. The proposed study will address important research questions concerning depression and cerebrovascular disease risk factors among older Mexican Americans, while providing a vehicle for the career development of the candidate.

描述（由申请人提供）：近 26% 的老年墨西哥裔美国人患有抑郁症状，但接受治疗的人很少（9.1%）。年长的墨西哥裔美国人患有糖尿病（33%）、高血压（62%）和抑郁症状的比例很高，这些都是与脑血管疾病相关的风险。随着拉丁裔人口数量的持续快速增长，拉丁裔脑血管疾病风险高、中风预防意识低，成为迫在眉睫的公共卫生问题。目前，人们对大多数未经治疗的抑郁症的病程和进展知之甚少，特别是因为它与这个庞大且快速增长的人群中的脑血管疾病有关。拟议研究计划的总体目标是开发和完善基于人群的纵向研究方法，研究抑郁症和脑血管疾病及其与老年墨西哥裔美国人认知和功能状态的关系。萨克拉门托地区拉丁裔老龄化研究 (SALSA) 是一项以人口为基础的纵向队列研究，研究对象为 1,789 名主要是墨西哥血统的老年拉丁裔。 SALSA 具有代表性样本，这使其成为研究与抑郁症相关的认知和功能障碍及衰退的预测因素的特别有价值的数据源。拟议的研究将解决有关老年墨西哥裔美国人抑郁症和脑血管疾病危险因素的重要研究问题，同时为候选人的职业发展提供工具。