Epidemiology of Late- Life Depression and Ethnicity Research Study

晚年抑郁症的流行病学和种族研究

• 批准号: 7736089
• 负责人: Hector M Gonzalez
• 金额: $ 40.38万
• 依托单位: WAYNE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-15 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7736089
• 关键词: 20 year old; Affect; Age; Aging; American; Back; Behavioral; Blood Vessels; Clinical; Cognitive; Country; Data; Data Set; Depressive disorder; Development; Diagnostic; Disadvantaged; Disease; Elderly; Environmental Risk Factor; Epidemiologic Studies; Epidemiology; Episodic memory; Ethnic Origin; Ethnic group; Future; Health Resources; Impairment; Intervention; Latino; Longevity; Major Depressive Disorder; Memory; Mental Health; Mental disorders; Minority Groups; National Institute of Mental Health; Neurobiology; Patient observation; Performance; Population; Prevalence; Prevention; Psyche structure; Psychopathology; Public Health; Recurrence; Research; Research Proposals; Respondent; Retirement; Risk; Risk Factors; Role; Sampling; Self Care; Societies; Strategic Planning; Testing; To specify; United States; Update; Work; aging population; burden of illness; cognitive function; depression; disability; ethnic minority population; evidence base; functional disability; functional status; geriatric depression; insight; meetings; middle age; new technology; preempt; public health relevance; racial and ethnic; research study

DESCRIPTION (provided by applicant): Epidemiology of late-life depression and ethnicity research study (ELLDERS) Currently, depression is a leading cause of disability in the United States and will continue to ascend in importance as the population continues to grow older over the coming decades. For older adults, national prevalence estimates of "true" depressive disorders meeting established diagnostic criteria date back to pioneer psychiatric epidemiologic work in the nineteen-eighties. Demographically, much has changed over the past twenty-years in the public health of the United States and internationally. Middle-aged "baby boomers" are now entering retirement age and Latinos, largely ignored until the turn of the millennium, are now the largest ethnic minority in the country. Additionally, new technologies have advanced our understanding and treatment of depression over the past two decades. Yet, most Americans with depression go untreated or undertreated, especially disadvantaged ethnic and racial minorities. Thoughtful work by Alexopoulos, Krishnan and others has relied on clinical observations and patient studies of to suggest late-life depression subtypes; however these subtypes have not been examined at the population level. Updated national estimates of "true" depressive disorders in older adults are needed to inform current and projected evidence-based allocations of appropriate mental health resources for an aging population. The products of this research application may offer insights for opportunities for late-life depression prevention in an aging and increasingly diverse United States population. PUBLIC HEALTH RELEVANCE: The project application (PA-07-082) titled the Epidemiology of late-life depression and ethnicity research study (ELLDERS) is a three-year study to examine the prevalence, risks, and burden of disease associated with late- life depression at the national level. Findings from the ELLDERS will provide updated estimates on the distribution of major depression and functional status of affected older adults in the United States. The products of this research application may offer insights for opportunities for late-life depression prevention in an aging and increasingly diverse United States population.

描述（由申请人提供）：晚年抑郁症流行病学和种族研究 (ELLDERS) 目前，抑郁症是美国残疾的主要原因，并且随着人口在未来几年继续老龄化，抑郁症的重要性将继续上升几十年。对于老年人来说，符合既定诊断标准的“真正的”抑郁症的全国患病率估计可以追溯到十九世纪八十年代的先驱精神病学流行病学工作。从人口统计学角度来看，过去二十年美国和国际公共卫生领域发生了很大变化。中年“婴儿潮一代”现在正进入退休年龄，而在世纪之交之前基本上被忽视的拉丁裔现在是该国最大的少数族裔。此外，在过去的二十年里，新技术促进了我们对抑郁症的理解和治疗。然而，大多数患有抑郁症的美国人都没有得到治疗或治疗不足，特别是弱势民族和少数族裔。 Alexopoulos、Krishnan 和其他人的深思熟虑的工作依赖于临床观察和患者研究来提出晚年抑郁症亚型；然而，这些亚型尚未在人群层面进行检查。需要更新国家对老年人“真正的”抑郁症的估计，以便为当前和预计的基于证据的老龄化人口适当心理健康资源分配提供信息。这项研究应用的产品可能会为老龄化和日益多样化的美国人口中预防晚年抑郁症的机会提供见解。公共卫生相关性：名为“晚年抑郁症流行病学和种族研究”(ELLDERS) 的项目申请 (PA-07-082) 是一项为期三年的研究，旨在检查与晚年抑郁症相关的疾病的患病率、风险和负担。全国范围内的生活萧条。 ELLDERS 的调查结果将为美国受影响的老年人重度抑郁症的分布和功能状态提供最新的估计。这项研究应用的产品可能会为老龄化和日益多样化的美国人口中预防晚年抑郁症的机会提供见解。