CORE--DATA MANAGEMENT AND COMPUTING

核心——数据管理和计算

• 批准号: 7212173
• 负责人: BENNETT DYKE
• 金额: $ 10.16万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7212173
• 关键词: animal genetic material tag; baboons; biomedical facility; computer data analysis; data collection; data collection methodology /evaluation; data management; data quality /integrity; genetic registry /resource /referral center; genotype; information systems; phenotype; tissue resource /registry

The objectives of the Data Management and Computing Core are to provide database management services for genotypic and phenotypic data used in this Program Project. This Core Unit also is responsible for data quality control, supports applications software, provides network and systems management for computers used by this Program Project, and protects the confidentiality and security of project data. Specific aims of this core unit during the proposed grant period are (1) to manage acquisition and control of computerized data used in this Program Project, and to maintain laboratory data acquisition software; (2) to maintain an inventory of samples collected in the course of the research; (3) to manage inter-laboratory file transfer; (4) to maintain the software used for processing gradient gel data; (5) to construct and maintain computerized pedigrees of family data; (6) to assess the quality of the data collected; (7) to manage and correct discrepant genotypes; (8) to calculate IBD matrices; (9) to transform raw data into forms suitable for genetic analysis; (10) to further develop and enhance software used in this Program Project as needed; (11) to undertake systems programming tasks as needed to maintain our computer system and its communications network; (12) to maintain system and data backup procedures; (13) to oversee system and network security; and (14) to establish a Web site for dissemination of information about this Program Project.

数据管理和计算核心的目标是为该程序项目中使用的基因型和表型数据提供数据库管理服务。 该核心单元还负责数据质量控制，支持应用程序软件，为该程序项目使用的计算机提供网络和系统管理，并保护项目数据的机密性和安全性。在拟议的赠款期间，该核心单位的具体目标是（1）管理该计划项目中使用的计算机数据的采集和控制，并维护实验室数据采集软件； （2）维持在研究过程中收集的样本的清单； （3）管理实验室间文件传输； （4）维护用于处理梯度凝胶数据的软件； （5）构建和维护 家庭数据的计算机谱系； （6）评估收集的数据的质量； （7）管理和纠正差异基因型； （8）计算IBD矩阵； （9）将原始数据转换为适合遗传分析的形式； （10）根据需要进一步开发和增强该程序项目中使用的软件； （11）根据需要执行系统编程任务，以维护我们的计算机系统及其通信网络； （12）维护系统和数据备份程序； （13）监督系统和网络安全； （14）建立一个 网站用于传播有关此程序项目的信息。