CORE--DATA MANAGEMENT AND COMPUTING

核心——数据管理和计算

• 批准号: 6412996
• 负责人: BENNETT DYKE
• 金额: $ 10.16万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-01-01 至 2001-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6412996
• 关键词: baboons; biomedical facility; computer data analysis; data collection; data collection methodology /evaluation; data management; family genetics; tissue resource /registry

The objectives of Core Unit B are to provide database management for genotypic and phenotypic data generated in laboratories at the Southwest Foundation Department of Genetics and for pedigrees associated with these data. Core B also is responsible for data quality control, supports applications software, provides network and systems management for computers used by this Program Project, and protects the confidentiality and security of project data. Specific aims of this core unit during the proposed grant period are (1) to manage acquisition and control of computerized data used in this Program Project, and to maintain laboratory data acquisition software; (2) to maintain an inventory of blood and tissue samples collected in the course of the research; (3) to manage inter-laboratory file transfer; (4) to process laboratory data and to maintain the software used for processing; (5) to construct and maintain computerized pedigrees of family data; (6) to control the quality of the data collected; (7) to process raw data into forms suitable for genetic analysis; (8) to manage the resolution of markers that fail to conform to Mendelian expectations in our pedigrees; (9) to manage the computation of IBD matrices on marker loci as they are developed; (10) to further develop and enhance software used in this Program Project; and (11) to undertake systems management tasks as needed to maintain our computer system and its communications network as its is applied to this Program Project, and to protect the integrity of data collected during the course of this research.

核心单元的目标是为数据库管理提供 西南实验室生成的基因型和表型数据 基金会遗传学系和与这些相关的血统 数据。核心B还负责数据质量控制，支持 应用程序软件，为网络和系统管理提供 该程序项目使用的计算机，并保护机密性 和项目数据的安全性。 在拟议的赠款期间，该核心单位的具体目标是 （1）管理在此使用的计算机数据的采集和控制 计划项目，并维护实验室数据采集软件； （2）维持收集在的血液和组织样本清单 研究过程； （3）管理实验室间文件传输； （4） 处理实验室数据并维护用于 加工; （5）构建和维护家庭的计算机系谱 数据; （6）控制收集的数据的质量； （7）处理原始 将适用于遗传分析的形式数据； （8）管理 解决不符合门德利期望的标记的解决方案 我们的血统书； （9）管理标记上的IBD矩阵的计算 开发的基因座； （10）进一步开发和增强软件 在此程序项目中使用； （11）进行系统管理 根据需要维护我们的计算机系统及其通信的任务 网络将其应用于此程序项目，并保护 在这项研究过程中收集的数据的完整性。