CORE--DATA MANAGEMENT AND COMPUTING

核心——数据管理和计算

基本信息

批准号：
6109654
负责人：
BENNETT DYKE
金额：
$ 42.63万
依托单位：
TEXAS BIOMEDICAL RESEARCH INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
起止时间：
1999-01-01 至 1999-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6109654
关键词：
baboons biomedical facility computer data analysis data collection data collection methodology /evaluation data management family genetics tissue resource /registry

项目摘要

The objectives of Core Unit B are to provide database management for genotypic and phenotypic data generated in laboratories at the Southwest Foundation Department of Genetics and for pedigrees associated with these data. Core B also is responsible for data quality control, supports applications software, provides network and systems management for computers used by this Program Project, and protects the confidentiality and security of project data. Specific aims of this core unit during the proposed grant period are (1) to manage acquisition and control of computerized data used in this Program Project, and to maintain laboratory data acquisition software; (2) to maintain an inventory of blood and tissue samples collected in the course of the research; (3) to manage inter-laboratory file transfer; (4) to process laboratory data and to maintain the software used for processing; (5) to construct and maintain computerized pedigrees of family data; (6) to control the quality of the data collected; (7) to process raw data into forms suitable for genetic analysis; (8) to manage the resolution of markers that fail to conform to Mendelian expectations in our pedigrees; (9) to manage the computation of IBD matrices on marker loci as they are developed; (10) to further develop and enhance software used in this Program Project; and (11) to undertake systems management tasks as needed to maintain our computer system and its communications network as its is applied to this Program Project, and to protect the integrity of data collected during the course of this research.

核心单元 B 的目标是提供数据库管理西南实验室生成的基因型和表型数据基金会遗传学系和与这些相关的谱系数据。 Core B还负责数据质量控制，支持应用软件，提供网络和系统管理本计划项目使用的计算机，并保护机密和项目数据的安全性。该核心单位在拟议拨款期内的具体目标是 (1) 管理本项目中使用的计算机化数据的获取和控制计划项目，并维护实验室数据采集软件； (2) 保存采集的血液和组织样本的库存研究过程；（三）管理实验室间文件传输； (4) 处理实验室数据并维护用于加工; (5)建立和维护计算机化的家族谱系数据; (6) 控制所收集数据的质量； (7) 原料加工数据转化为适合遗传分析的形式； (8) 管理不符合孟德尔期望的标记的分辨率我们的血统； (9) 管理标记上 IBD 矩阵的计算基因座的发育； (10)进一步开发和增强软件用于本计划项目；（十一）进行系统管理维护我们的计算机系统及其通信所需的任务网络应用于本计划项目，并保护本研究过程中收集的数据的完整性。