CBT/Comorbid Anxiety Disorders/Children/Asperger Syndro*

CBT/共病焦虑症/儿童/阿斯伯格综合症*

基本信息

批准号：
7015991
负责人：
Jeffrey James Wood
金额：
$ 7.73万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-09-23 至 2007-08-31
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): Anxiety disorders are commonly diagnosed in children with Asperger syndrome (AS) and pervasive developmental disorder not otherwise specified (PDD-NOS). Anxiety disorders contribute to children's functional impairment over and above the functional deficits attributable to AS and PDD-NOS. Thus, investigators have called for the development of anxiety treatments for this population (Attwood, 2003). Cognitive behavioral therapy (CBT) has been found to be efficacious for anxiety disorders in typically developing children. This pilot study will advance the field by providing an estimate of the treatment effects of CBT for anxiety disorders among children with AS or PDD-NOS. The sample will include 20 children aged 7- 13 years with AS or PDD-NOS and a comorbid anxiety disorder. Children will be randomly assigned to immediate treatment or a 3-month waitlist. The manualized CBT program includes traditional anxiety treatment components including coping skills training (e.g., cognitive restructuring), in vivo exposure, operant procedures, and parent training. Additional treatment components have been added to enhance intervention response in children with AS or PDD-NOS, including emotion education, social skills/friendship skills training, and peer tutoring/mentoring modules. Trained graduate students with expertise in CBT and developmental disabilities will serve as therapists. Treatment fidelity will be checked using a session-by-session adherence checklist. Treatment acceptability and consumer satisfaction will be assessed at posttreatment, providing guidance on the extent to which the manual will need to be revised. Multiple measures of children's anxiety, including a structured diagnostic interview administered by an independent evaluator, will comprise the primary outcomes. Children's social functioning and service use will also be assessed to determine if CBT can affect relevant distal outcomes. By comparing outcomes for children in the immediate treatment group versus those in the waitlist group, we will estimate effect sizes of CBT for this population. Subsequently, power analyses will be conducted in planning for a larger clinical trial. This study could contribute to public health efforts to address the mental health needs of the rising number of children diagnosed with autism spectrum disorders. If CBT is found to be efficacious, it will be the first evidence-based psychological treatment to be successfully adapted for children with AS and PDD-NOS.

描述（由申请人提供）：焦虑症通常在患有阿斯伯格综合症（AS）和未另行指定的广泛性发育障碍（PDD-NOS）的儿童中被诊断出来。除了 AS 和 PDD-NOS 造成的功能缺陷之外，焦虑症还会导致儿童功能障碍。因此，研究人员呼吁开发针对这一人群的焦虑疗法（Attwood，2003）。认知行为疗法（CBT）已被发现对正常发育儿童的焦虑症有效。这项试点研究将评估 CBT 对 AS 或 PDD-NOS 儿童焦虑症的治疗效果，从而推动该领域的发展。样本将包括 20 名 7-13 岁患有 AS 或 PDD-NOS 以及共病焦虑症的儿童。儿童将被随机分配接受立即治疗或 3 个月的等待治疗。手动认知行为治疗项目包括传统的焦虑治疗成分，包括应对技能训练（例如认知重建）、体内暴露、操作程序和家长培训。添加了额外的治疗成分，以增强 AS 或 PDD-NOS 儿童的干预反应，包括情绪教育、社交技能/友谊技能培训和同伴辅导/指导模块。经过培训、具有 CBT 和发育障碍专业知识的研究生将担任治疗师。将使用逐个疗程的依从性检查表来检查治疗保真度。治疗可接受性和消费者满意度将在治疗后进行评估，为手册需要修订的程度提供指导。主要结果将包括对儿童焦虑的多种测量，包括由独立评估员进行的结构化诊断访谈。还将评估儿童的社会功能和服务使用情况，以确定 CBT 是否会影响相关的远端结果。通过比较立即治疗组和候补组儿童的结果，我们将估计 CBT 对这一人群的效果大小。随后，将进行功效分析以规划更大规模的临床试验。这项研究可能有助于公共卫生工作，以满足越来越多的被诊断患有自闭症谱系障碍的儿童的心理健康需求。如果 CBT 被证明有效，这将是第一个成功适用于 AS 和 PDD-NOS 儿童的循证心理治疗方法。