2006 Mechanisms of epilepsy and neuronal synchronization Gordon Conference

2006年癫痫和神经元同步机制戈登会议

• 批准号: 7113454
• 负责人: Kevin J. Staley
• 金额: $ 1.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7113454
• 关键词: disease /disorder etiology; epilepsy; meeting /conference /symposium; travel

DESCRIPTION (provided by applicant): We are requesting NINDS support for a first-time Gordon Research Conference on Mechanisms of epilepsy and neuronal synchronization to be held Aug 6-11, 2006 at Colby College in Maine. The main goal of the study of seizures is to identify the mechanisms underlying synchronous electrical discharges in neuronal networks in order to develop more effective and less toxic treatments and cures for epilepsy. A unique, intellectually challenging aspect of epilepsy research arises from the fact that it encompasses virtually all major levels of biological organization, from genes and ion channels to circuits and behavior. The major purpose of this Gordon conference is to bring together geneticists, molecular biologists, developmental neuroscientists, neuroanatomists, electrophysiologists and computational neuroscientists working on basic mechanisms related either directly or indirectly to seizure generation to synthesize current advances and to set the stage for future discoveries. Topics to be covered include Gene expression profiling in epilepsy, Epileptogenic ion channels, Epileptogenic dysgenesis, Homeostatic plasticity, Structural reorganization in epilepsy, Hypersynchrony and non-linear dynamics, Gap junctions, Key events underlying epileptogenesis, and Entorhinal-hippocampal interplay in epilepsy. Our goals are to disseminate the latest scientific advances, foster productive new insights and collaborations, and set the stage for new translational studies that will bring the newest discoveries to the bedside in the shortest possible time.

描述（由申请人提供）：我们要求NINDS支持首次在2006年8月6日至11日在缅因州的Colby College举行的有关癫痫机制和神经元同步机制的研究会议。 癫痫发作研究的主要目的是确定神经元网络中同步电气放电的机制，以开发出更有效，更少的毒性治疗方法和癫痫病的治疗方法。 癫痫研究的独特，智力上具有挑战性的方面源于以下事实：它几乎涵盖了从基因和离子渠道到电路和行为的几乎所有主要级别的生物组织。 这次戈登会议的主要目的是将遗传学家，分子生物学家，发育神经科学家，神经解剖学家，电生理学家和计算神经科学家直接或间接地与癫痫发作相关的基本机制，从而为当前的进步并为未来的发现建立舞台。 要涵盖的主题包括癫痫，癫痫发电通道，癫痫发育失调，稳态可塑性，癫痫结构重组，癫痫，非线性动力学，间隙连接，间隙连接，关键事件，癫痫发作和Intorhinal-Hippypocampal Interplepsy insplay insepsy。 我们的目标是传播最新的科学进步，促进生产力的新见解和合作，并为新的翻译研究奠定了基础，这些研究将在最短的时间内将最新的发现带到床边。