TOXIC INTERACTIONS OF AIR POLLUTANT COMPOUNDS

空气污染物的毒性相互作用

• 批准号: 7170727
• 负责人: MICHAEL P DOHM
• 金额: $ 13.8万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7170727
• 关键词: biomedical facility; biomedical resource; cell biology; clinical research; health science research support; immunopathology; nervous system disorder

DESCRIPTION (provided by applicant): Building upon the network foundation established by BRIN, INBRE proposes to expand and to develop Hawaii's competitive biomedical research capacity. The expansion will center on three thematic projects exploring the cellular basis of immunological and neurological diseases from the perspective of immunology, cell biology, and developmental biology. Each project will be led by a well-established senior investigator who will mentor junior investigators at both the lead and the affiliated baccalaureate institutions. This will extend into the state's community colleges where participating faculty will collaborate with established researchers at the lead institution. Each investigator - senior, junior, and Outreach - will recruit and mentor undergraduate and graduate students as well. The development will concentrate on not only individual research careers but also the network's overall approach to competitive research. This involves the establishment of rigorous standards and performance expectations coupled with attentive mentoring to assist network investigators and students in meeting these challenging criteria. Organizationally, INBRE will consist of four major cores: Administrative, Research, Bioinformatics, and Outreach. The Administrative Core will provide overall administrative support, including maintenance of the network's web site, evaluation efforts, and training and mentoring workshops and seminars. The Research Core will be comprised of the three thematic research projects with a Core leader to ensure project coordination. The Outreach Core extends the research thrust into the community colleges by promoting research and student participation through collaborations with the lead and the baccalaureate institutions. The Bioinformatics Core will also provide unique opportunities by emphasizing academic work force development. To facilitate this, the Core will be housed within the University of Hawaii at Manoa's Department of Information and Computer Sciences.

描述（由申请人提供）：基于Brin建立的网络基础，Inbre提议扩展和发展夏威夷的竞争性生物医学研究能力。扩展将集中在三个主题项目上，从免疫学，细胞生物学和发育生物学的角度探索免疫和神经系统疾病的细胞基础。每个项目将由一位成熟的高级调查员领导，他们将指导铅和附属学士学位机构的初级调查员。这将扩展到该州的社区学院，参与学院将与著名研究人员合作。每个调查员 - 高级，初中和外展 - 也将招募和导师本科生和研究生。该发展不仅将集中在个人研究事业上，还集中于网络的竞争研究总体方法。这涉及建立严格的标准和绩效期望以及细心的指导，以帮助网络调查人员和学生满足这些具有挑战性的标准。在组织上，近亲会 由四个主要核心组成：行政，研究，生物信息学和外展。行政 核心将提供总体行政支持，包括维护网络的网站，评估工作以及培训和指导研讨会和研讨会。研究核心将由三个主题研究项目和核心领导者组成，以确保项目协调。外展核心通过与领导和学士学位机构的合作来促进研究和学生的参与，将研究推进到社区大学。生物信息学核心还将通过强调学术劳动力发展来提供独特的机会。为了促进这一点，核心将安置在夏威夷大学信息与计算机科学系中。