Early Childhood Autism Surveillance

儿童早期自闭症监测

• 批准号: 7167932
• 负责人: JUDITH Susanne MILLER
• 金额: $ 12.5万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7167932
• 关键词: autism; behavioral /social science research tag; clinical research; cooperative study; data collection methodology /evaluation; diagnosis design /evaluation; early diagnosis; human subject; mental disorder diagnosis; mental health epidemiology; preschool child (1-5)

DESCRIPTION (provided by applicant): Public concern about Autism Spectrum Disorders has been fueled by reports of increased prevalence in school age and preschool children. While the onset of ASD is within the first36 months of life, prevalence during the first 3 years of life is not established. This proposal aims to develop and pilot test methods for ASD surveillance in early childhood, in preparation for a subsequent prevalence study of a single year birth cohort. Emerging data indicate that autism can be identified in children under age 3. However, whether it is evident in the 1st, 2nd, or 3rd year of life can vary, especially if the child experiences a developmental regression. The current application presents a design for a population-based prevalence study that would follow children from ages 18-36 months for a 2 year period, with repeated screenings throughout to capture children as their autism manifests. Specific aims for the current proposal are to pilot test this screening approach, and to establish the relationships and data linkages necessary to conduct the full prevalence study. In addition, we will complete the record review methods used in other CDC prevalence studies and compare case rates between direct screening and record review only to determine whether record review alone is sufficient in this age range. This study responds to several of the priorities outlined by the lnteragency Autism Coordinating Committee, including a call for intensive, community-based prevalence studies with clinical evaluations that can be repeated over time to determine changes in prevalence, methods to develop community-based screening of very young children, and testing of screening tools. This application builds on a foundation of Utah research on autism that includes: ADDM network Study Year 2002; an established relationship between the University and the Health Department; widespread community support for autism research; and a strong University research environment.

描述（由申请人提供）：公众对自闭症谱系障碍的关注是由于学龄前儿童和学龄前儿童患病率增加的报道所推动的。尽管ASD的发作在生命的前36个月内，但在生命的前三年中的流行尚未确定。该提案旨在开发和试行童年时期ASD监视的方法，以准备对单年出生队列进行随后的患病率研究。新兴的数据表明，在3岁以下的儿童中可以识别自闭症。但是，无论是在第一年，第二年还是第三年都可以明显看出自闭症，尤其是如果儿童经历了发育回归。当前的申请为基于人群的患病率研究提供了设计，该研究将跟随2年的18-36个月的儿童，并在整个过程中重复筛查，以捕获儿童作为自闭症的表现。当前建议的具体目的是试点测试这种筛选方法，并建立进行完整的患病率研究所需的关系和数据链接。此外，我们将完成其他CDC患病率研究中使用的记录审查方法，并比较直接筛选和记录审查之间的病例率，以确定在此年龄范围内单独的记录审查是否足够。这项研究回应了LNTeragency自闭症协调委员会概述的几个优先事项，包括呼吁对临床评估进行临床评估的强化，基于社区的患病率研究，以确定患病率的变化，开发基于社区的筛查的方法，以开发非常年幼的孩子的筛查以及筛查工具的测试。该应用程序建立在犹他州自闭症研究基础的基础上，其中包括：ADDM网络研究年度； 2002年；大学与卫生部门之间建立的关系；广泛的社区支持自闭症研究；以及强大的大学研究环境。