BLOCKING VIRUS SPREAD BY DCS WITH CARRAGEENAN-BASED COMPOUNDS

用卡拉胶基化合物阻断 DCS 传播的病毒

• 批准号: 7165062
• 负责人: Melissa J Robbiani
• 金额: $ 5.25万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7165062
• 关键词: Primates; animal colony

DESCRIPTION (provided by applicant): This application requests funding for the TNPRC for the five-year period beginning May 1, 2003 through April 30, 2008. Funds will be used to support the administration, operations, veterinary resources, and scientific research resources of the Center. Additional funds to support pilot research projects and colony-health-related research resource projects are also requested. The research program at the TNPRC has been focused on infectious disease research for close to three decades. Although the majority of the Center's research efforts are devoted to infectious disease, there are also rapidly expanding programs in gene therapy and assisted reproductive technologies (ART). The infectious disease program currently focuses on AIDS, Malaria Microsporidial diseases, and Lyme disease. These are multidisciplinary studies involving investigators in numerous Divisions at the TNPRC as well as collaborators outside the Center. The studies cover the spectrum from transmission, diagnosis and pathogenesis, development of vaccine strategies and chemotherapeutic treatments, and pathologic lesions to gene sequences. In addition, the development of the gene therapy program allows for novel approaches to the treatment of many types of disease and preclinical modeling of a variety of gene therapy modalities. The last five years, and particularly the last year, have seen significant changes at the Center, following the retirement of Dr. Peter Gerone and the naming of Dr. Andrew Lackner as the new Director. Since October 1, 2001 when Dr. Lackner became Director, leadership in several of the Divisions has changed, new Divisions have been formed, and the business office (now Administrative Services) has begun reorganization. The result is a Center that now places more emphasis on research programs and which has experienced a 50% growth in its grant portfolio. These changes have been facilitated by a very helpful and collegial host institution. The new organizational structure and leadership team at the TNPRC and recent successes in obtaining grant funding and attracting outside collaboration suggest that the Center is poised for a period of significant growth and improvement.

描述（由申请人提供）： 该申请要求从2003年5月1日到2008年4月30日开始为TNPRC提供资金。资金将用于支持该中心的管理，运营，兽医资源和科学研究资源。 还要求提供其他资金来支持试点研究项目和与殖民地健康相关的研究资源项目。 TNPRC的研究计划一直集中在传染病研究上已有近三十年了。 尽管该中心的大部分研究工作都致力于传染病，但基因疗法和辅助生殖技术（ART）也有迅速扩大的计划。 传染病计划目前侧重于艾滋病，疟疾微孢子虫疾病和莱姆病。 这些是多学科研究，涉及TNPRC众多部门的研究人员以及中心外的合作者。 该研究涵盖了传播，诊断和发病机理，疫苗策略和化学治疗的发展以及基因序列的病理病变的光谱。 此外，基因疗法计划的发展允许对多种基因治疗方式的多种疾病和临床前建模进行新的方法。 在彼得·杰罗纳（Peter Gerone）博士退休后，在中心发生了重大变化，安德鲁·布莱斯纳（Andrew Lackner）命名为新任董事。 自2001年10月1日以来，当Lackner博士成为董事时，在几个部门的领导中发生了变化，已经形成了新的部门，并且商业办公室（现在的行政服务）已经开始重组。 结果是一个中心，现在更加重视研究计划，并且其赠款投资组合增长了50％。 这些变化已由一个非常有用的大学主持机构促进。 TNPRC的新组织结构和领导团队以及获得赠款资金和吸引外部协作的最新成功表明，该中心有望为一段显着的增长和改善时期。