Low-Cost Device for Digital Retinal Imaging

用于数字视网膜成像的低成本设备

• 批准号: 7061129
• 负责人: ANN E ELSNER
• 金额: $ 18.63万
• 依托单位: TRUSTEES OF INDIANA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-05 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7061129
• 关键词: adult human (21+); bioengineering /biomedical engineering; bioimaging /biomedical imaging; biomedical equipment development; digital imaging; eye disorder diagnosis; human subject; imaging /visualization /scanning; lasers; macular degeneration; pupillography; retina; retinography

DESCRIPTION (provided by applicant): We plan a low cost, simple-to use-device for imaging the human macula in a broad variety of patients, a Laser Scanning Digital Camera (LSDC). Our goal is for the basic LSDC to have an up front, one-time cost less than 10% of the total price of current high end devices, without a decrement in image quality but with superior ease of use. The resulting LSDC should be considered as much an ophthalmoscope as a camera, since current ophthalmoscopes are often poorly used by non eye-care specialists. This work is derived from over 15 years of experience in imaging the human retina with a comfortable and safe level of near infrared light, as well as visible wavelength light, using laboratory instrumentation built by the P.I. Commercially developed instruments in a clinical setting led to further applications. It became clear that a digital retinal imaging device was needed that does not require the use of eye drops to dilate the pupils. This led to considerable thought about what features were absolutely necessary, and how such a device could be simplified over commercially available instruments. The LSDC will work like an off-the-shelf digital camera for use by non-experts in the eye care field. It will be operated in a non-invasive, non-contact manner, without the need for drops to dilate the pupil of the eye. Our usability studies indicated that without training, even physicians could not determine the procedure to use high-end instruments: they wasted a large amount of time staring at the computer screen, where no directions appeared. Ease of use is improved by eliminating the dedicated ancillary computer and image acquisition system, which require supporting electronics and proprietary computer software. Device complexity, weight, size, and consequently cost are also reduced. A device is truly low-cost only if it can withstand use and minimal training for use is needed. Thus, cords and external power supplies that are easily broken will eliminated, and the planned device can be ruggedly packaged. Our proposed digital camera approach, combined with an onboard and web-based database of eye diseases, reduces training to almost a cook-book approach. This proposal builds our initial work aimed a trauma to include a broader range of maculopathies, including those affecting adults and pediatric patients. The broader range of eye problems and the smaller eye size of children require instrumentation research in the optimization of optics and construct validity. Finally, we will examine the image quality of this low cost LSDC for functions such as angiography.

描述（由申请人提供）： 我们计划开发一种低成本、易于使用的设备，用于对各种患者的人类黄斑进行成像，即激光扫描数码相机 (LSDC)。我们的目标是使基本 LSDC 的一次性一次性成本低于当前高端设备总价的 10%，且不会降低图像质量，但具有卓越的易用性。由此产生的 LSDC 应被视为与相机一样的检眼镜，因为非眼科护理专家通常很少使用当前的检眼镜。这项工作源自超过 15 年的经验，使用 P.I. 建造的实验室仪器，使用舒适且安全的近红外光以及可见波长光对人类视网膜进行成像。在临床环境中商业开发的仪器带来了进一步的应用。很明显，需要一种不需要使用眼药水来扩张瞳孔的数字视网膜成像设备。这导致人们深入思考哪些功能是绝对必要的，以及如何在商用仪器上简化此类设备。 LSDC 将像现成的数码相机一样工作，供眼保健领域的非专家使用。它将以非侵入性、非接触的方式进行操作，无需滴眼药水来扩张眼睛的瞳孔。我们的可用性研究表明，未经培训，即使是医生也无法确定使用高端仪器的程序：他们浪费了大量时间盯着没有任何指示的电脑屏幕。通过消除需要支持电子设备和专有计算机软件的专用辅助计算机和图像采集系统，提高了易用性。设备复杂性、重量、尺寸以及成本也都降低了。只有能够承受使用并且需要最少的使用培训的设备才是真正的低成本设备。因此，将消除容易损坏的电线和外部电源，并且可以对计划的设备进行坚固的封装。我们提出的数码相机方法与机载和基于网络的眼病数据库相结合，将培训减少到几乎是食谱方法。该提案建立了我们的初步工作，旨在将创伤纳入更广泛的黄斑病，包括影响成人和儿童患者的黄斑病。更广泛的眼部问题和儿童较小的眼睛尺寸需要在光学优化和结构有效性方面进行仪器研究。最后，我们将检查这种低成本 LSDC 的图像质量，以实现血管造影等功能。