Club Drug Use and HIV Risks among Minorities in NYC

纽约市少数族裔俱乐部吸毒和艾滋病毒风险

• 批准号: 7088872
• 负责人: DANIELLE C OMPAD
• 金额: $ 71.41万
• 依托单位: NEW YORK ACADEMY OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7088872
• 关键词: 3,4 methylenedioxymethamphetamine; HIV infections; clinical research; cocaine; communicable disease control; communicable disease transmission; disease /disorder proneness /risk; drug abuse; ethnic group; family structure /dynamics; geographic difference; hepatitis C; heroin; high risk behavior /lifestyle; human population study; human subject; inhalation drug abuse; intravenous drug abuse; ketamine; lysergic acid diethylamide; peer group; phencyclidine; racial /ethnic difference; sex behavior; socioeconomics; substance abuse related behavior

DESCRIPTION (provided by applicant): The purpose of this cross-sectional study is to determine the prevalence, correlates and sequelae of club drug use among an economically disadvantaged, racial/ethnically diverse population of substance users in New York City (NYC) in order to provide information on the associations between use of club drugs and high risk sexual behavior in this population. This information can be instrumental to comprehensive substance abuse and HIV prevention efforts in economically disadvantaged communities. Club drug use [a collective term for ecstasy, GHB, ketamine, LSD, methamphetamines, PCP, and flunitrazepam] is increasing in NYC based on data from indicator surveillance, the medical examiner, and hospital reports. In our ongoing surveys of injection drug users in Harlem, a higher number of lifetime sex partners was seen among the 30% with lifetime use of LSD and PCP. While sexual risks with heroin and cocaine in their various forms has been characterized in minority inner city communities, the degree to which club drugs, alone or in combination with other illicit drugs, are independently associated with risky sexual behavior and infections remains an open question. In this study we will enroll 2000 substance users using systematic recruitment techniques in eight disadvantaged neighborhoods within four boroughs of NYC. Eligible and consenting participants will undergo an interview and specimen collection. The study will address three aims: (1) to estimate the prevalence of club drugs (separately and combined) among persons who report injection and non-injection drug use, and to report personal characteristics (e.g. demographics, other illicit drug use), place (e.g., by neighborhood) and time (e.g., time trends within a multi-year sampling scheme) factors associated with club drug use; (2) to identify and compare the predisposing factors (e.g., availability, opportunity, family and peer influences, neighborhood characteristics) and specific circumstances of initiation and subsequent purchases of club drugs and to compare these factors for club drug use separately whether or not participants use inhaled or injectable forms of heroin, cocaine alone or together; (3) to identify and compare sexual risk behaviors among club drug users and non-club drug users in a population defined by active heroin, crack or cocaine use, after accounting for other covariates; and (4) to identify and compare the HIV and HCV seroprevalence among club drug users and non-club drug users.

描述（由申请人提供）：这项横断面研究的目的是确定纽约市经济上不利的，种族/种族多样化的毒品使用者（NYC）的普遍性，相关和后遗症，以提供有关俱乐部药物使用与高风险性行为的关联的信息。这些信息可能对经济不利的社区中的全面药物滥用和预防艾滋病毒的预防工作有用。俱乐部毒品使用[摇头丸，GHB，氯胺酮，LSD，甲基苯丙胺，PCP和Flunitrazepam的集体术语]根据指标监视，体育检查员和医院的报告，纽约市的纽约市正在增加纽约市的狂热术语。在我们正在进行的Harlem注射吸毒者的调查中，在使用LSD和PCP的终生使用中，有30％的终身性伴侣被发现。 尽管在少数民族内城市社区中，海洛因和可卡因的性风险已被描述为各种形式，但俱乐部毒品独立或与其他非法药物结合的程度与风险的性行为和感染是独立的，仍然是一个悬而未决的问题。 在这项研究中，我们将使用系统的招聘技术在纽约市四个行政区内的八个处境不利的社区中使用2000种药物使用者。 符合条件和同意的参与者将接受面试和标本收集。 该研究将针对三个目标：（1）估计报告注射和非注射药物使用的人的俱乐部药物（分别和合并）的普遍性，并报告个人特征（例如人口统计学，其他非法药物使用），位置（例如，邻里）和时间（例如，时间）和时间（例如，与俱乐部相关的多年采样计划中的时间趋势）； （2）识别和比较诱发因素（例如可用性，机会，家庭和同伴影响，邻里特征，邻里特征）以及启动的特定情况以及随后购买俱乐部毒品的购买，并分别比较这些因素，无论参与者是否会单独使用Inhaled或Discoble -docutsing foremants毒品使用； （3）在考虑其他协变量后，在主动海洛因，破解或可卡因使用的人群中，俱乐部吸毒者和非俱乐部吸毒者的性风险行为； （4）识别和比较俱乐部吸毒者和非俱乐部吸毒者的艾滋病毒和HCV血清阳性。