SURE (SUMMER UNDERGRADUATE RESEARCH EXPERIENCE) PROGRAM

SURE（暑期本科生研究经历）项目

• 批准号: 6708899
• 负责人: CHRISTOPHER S FRANCKLYN
• 金额: $ 7.24万
• 依托单位: UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-03-01 至 2005-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6708899
• 关键词: career; health science research potential; physical science; science education; training; university student

Over the last decade, many graduate programs in biochemistry have experienced a decline in the number of applicants with backgrounds in which the quantitative aspects of sciences are stressed, which is typical of the physical sciences. In order to address this problem, we propose to create a Summer Undergraduate Research Experience (SURE) in the Department of Biochemistry at the University of Vermont. The immediate objective is to introduce qualified undergraduates with a physical sciences background to biomedical research questions and techniques under the direction of 11 faculty with a diverse array of research interests, including protein-protein interactions in the blood coagulation cascade, metalloprotein biochemistry, protein crystallography, protein-nucleic acid interactions, and structure and function of protein complexes. The trainees will be selected on the basis of their previous coursework and undergraduate sponsor's recommendations from an ensemble of colleges and universities in the Northeast where we have successfully recruited in the past. The aims of the training program are to 1) recruit, train, and mentor 6-10 promising undergraduates through sponsored independent research in the laboratories of NIH-funded training faculty; 2) augment the independent research experience with lectures, seminars, and workshops to build foundation knowledge and stimulate critical thinking; and 3) evaluate the program through a four step process involving: a) assessment of incoming student qualifications; b) assessment of student progress and reaction in situ; c) summative assessment at the conclusion of the program; and d) follow-up assessment to determine the impact of the experience on the participant's careers. By providing a positive training experience for physical science undergraduates in a highly focused context, we anticipate that the SURE program will both increase the pool of potential applicants to the University of Vermont's biomedical graduate programs, as well as the pool of potential applicants nationwide.

在过去的十年中，许多生物化学研究生项目的申请者数量出现了下降，这些项目的背景是强调科学的定量方面，这是物理科学的典型特征。为了解决这个问题，我们建议在佛蒙特大学生物化学系创建暑期本科生研究体验（SURE）。近期目标是在 11 名具有不同研究兴趣的教师的指导下，向具有物理科学背景的合格本科生介绍生物医学研究问题和技术，包括凝血级联中的蛋白质-蛋白质相互作用、金属蛋白生物化学、蛋白质晶体学、蛋白质-核酸相互作用以及蛋白质复合物的结构和功能。学员将根据他们之前的课程作业和本科生赞助商的推荐从我们过去成功招募的东北地区的一些学院和大学中进行选择。培训计划的目的是 1) 通过在 NIH 资助的培训教师实验室中进行独立研究来招募、培训和指导 6-10 名有前途的本科生； 2）通过讲座、研讨会和讲习班增强独立研究经验，以建立基础知识并激发批判性思维； 3) 通过四步流程评估课程，包括： a) 评估新生资格； b) 现场评估学生的进步和反应； c) 计划结束时的总结性评估； d) 后续评估以确定该经历对参与者职业生涯的影响。通过在高度集中的背景下为物理科学本科生提供积极的培训体验，我们预计 SURE 项目将增加佛蒙特大学生物医学研究生项目的潜在申请人数量，以及全国范围内的潜在申请人数量。