MBRS Program-University of Southern Colorado

MBRS项目-南科罗拉多大学

• 批准号: 6787708
• 负责人: Sandra Bonetti
• 金额: $ 23.8万
• 依托单位: COLORADO STATE UNIVERSITY-PUEBLO
• 依托单位国家: 美国
• 财政年份: 1981
• 资助国家: 美国
• 起止时间: 1981-08-25 至 2006-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6787708
• 关键词: MBRS; Program; University; Southern; Colorado

DESCRIPTION (provided by applicant): This proposal requests support for a new SCORE Program to replace the existing, traditional MBRS grant at the University of Southern Colorado (USC). The three departments participating in this new SCORE application are the Departments of Biology, Chemistry, and Psychology; each of these departments has submitted two research subprojects. The overall goals of this program are to enhance institutional biomedical research capabilities and to attract and recruit underrepresented minority participation in the biomedical research enterprise. The individual and program goals support this mission. The specific goals of the overall program are as follows: (1) to increase the research competitiveness or productivity of SCORE research faculty in the Departments of Biology, Chemistry, and Psychology; and (2) to increase the participation of faculty and students on campus, especially minorities, in biomedical research. Measurable objectives and activities accompany each of these goals. For the first specific goal, productivity will be measured in terms of numbers of refereed presentations, publications, grant submissions, and collaborations. A specific standard of 3 publications and 10 presentations has been instituted as the minimum standard for the SCORE Program subprojects. For the second specific activity, the number of supplemental applications to SCORE and participation of USC faculty in grantmanship workshops, seminars, and faculty research roundtables will be used to assess the achievement of the goal. An evaluation plan and an external advisory committee are vital components of this grant and will enhance the activities proposed and will promote the completion of the goals. To achieve the overall SCORE program goals, six subprojects and an administrative component are participating in this grant. The six research projects include two in Biology, two in Chemistry, and two in Psychology. One of the biology projects examines the mechanisms of psoralen-induced reproductive toxicity. The second biology project, a reproductive physiology project, is a comparative study of events surrounding the zona escape in mammals. The Chemistry projects are in Biochemistry and Analytical Chemistry. The biochemistry project examines fungal cell surfaces by using standard chemical methods and the recently developed technique of atomic force microscopy, with the potential of providing valuable information for the design of antifungal agents. The analytical project characterizes novel silica surfaces that may be potentially used in separation of complex biological mixtures and pharmaceuticals. One of the Psychology projects examines the interactions of peptides with alcohol satiation and the second investigates the relationship between reading disabilities in children and neuroanatomy.

描述（由申请人提供）：该提案请求支持新的 SCORE 计划，以取代南科罗拉多大学 (USC) 现有的传统 MBRS 资助。参与这个新 SCORE 应用程序的三个系是生物系、化学系和心理学系；每个部门都提交了两个研究子项目。该计划的总体目标是增强机构生物医学研究能力，并吸引和招募代表性不足的少数群体参与生物医学研究企业。个人和计划目标支持这一使命。总体计划的具体目标如下：（1）提高生物系、化学系和心理学系SCORE研究人员的研究竞争力或生产力； (2) 增加校园教师和学生，特别是少数族裔学生对生物医学研究的参与。每个目标都伴随着可衡量的目标和活动。对于第一个具体目标，生产力将根据经过评审的演示文稿、出版物、拨款申请和合作的数量来衡量。 SCORE 计划子项目的最低标准是制定 3 份出版物和 10 份演示文稿的具体标准。对于第二项具体活动，将根据 SCORE 的补充申请数量以及南加州大学教师参加资助研讨会、研讨会和教师研究圆桌会议的数量来评估目标的实现情况。评估计划和外部咨询委员会是这笔赠款的重要组成部分，将加强拟议的活动并促进目标的完成。为了实现 SCORE 计划的总体目标，六个子项目和一个行政部分参与了这笔赠款。这六个研究项目包括两个生物学、两个化学和两个心理学。其中一项生物学项目研究了补骨脂素引起的生殖毒性的机制。第二个生物学项目是生殖生理学项目，是对哺乳动物逃逸透明带事件的比较研究。化学项目属于生物化学和分析化学。该生物化学项目通过使用标准化学方法和最近开发的原子力显微镜技术来检查真菌细胞表面，有可能为抗真菌剂的设计提供有价值的信息。该分析项目表征了可能用于分离复杂生物混合物和药物的新型二氧化硅表面。其中一个心理学项目研究了肽与酒精饱腹感之间的相互作用，第二个项目研究了儿童阅读障碍与神经解剖学之间的关系。