Signal Processing And Instrumentation Section

信号处理和仪器部分

• 批准号: 6988051
• 负责人: THOMAS J POHIDA
• 金额: --
• 依托单位: CENTER FOR INFORMATION TECHNOLOGY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6988051
• 关键词: atomic force microscopy; biological signal transduction; computer program /software; computer system design /evaluation; functional magnetic resonance imaging; human subject; laser capture microdissection; microarray technology; positron emission tomography; technology /technique development; telemetry

The Signal Processing and Instrumentation Section (SPIS) provides electrical, electronic, electro-optical, computer, and software engineering expertise to the NIH Intramural Research program for projects that require the development of biomedical instrumentation and signal processing systems. These SPIS collaborations involve advanced real-time signal transduction, signal processing, and control systems; and result in the creation of new biomedical instrumentation technologies. Example technology developments and projects include: cDNA and protein microarray; tissue microarray; laser capture microdissection (LCM); expression microdissection (xMD); chromosome microdissection; microfluidics, microfabrication, and microanalysis; single molecule, DNA, and chromatin fiber mechanics and manipulation; high-speed scanning spectrometry; atomic force microscopy (AFM); electron paramagnetic resonance (EPR) imaging; magnetic resonance imaging (MRI) and functional MRI (fMRI) methodologies and devices; magnetic resonance elastography (MRE) imaging; ultrasound imaging; positron emission tomography (PET) imaging; infrared fluorescence imaging; speech acquisition and real-time adaptive processing; mouse pain model; and sinus cavity acoustic characterization. These SPIS capabilities and accomplishments have established the group as the focal point for this type of electrical engineering research and development at the NIH. The research and development activities of the section are collaborative efforts with NIH Institute scientists, and often result in the development of unique, specialized biomedical instruments. Other projects involve signal processing algorithm development required for system simulation and signal analysis. Section goals necessitate design expertise in advanced analog and digital circuitry, biophysical signal transduction techniques, radio-frequency and telemetry systems, digital signal processing hardware and software, programmable logic devices, printed circuit board development, opto-electronics, and computer based instrumentation for signal processing and control.

信号处理和仪器部分（SPI）为需要开发生物医学仪器和信号处理系统的项目的NIH壁内研究计划提供电气，电子，电脑，计算机和软件工程专业知识。这些SPI协作涉及高级实时信号转导，信号处理和控制系统。并导致创建新的生物医学仪器技术。示例技术开发和项目包括：cDNA和蛋白质微阵列；组织微阵列；激光捕获微分解（LCM）；表达微分解（XMD）;染色体显微解剖；微流体，微分析和微分析；单分子，DNA和染色质纤维力学和操纵；高速扫描光谱；原子力显微镜（AFM）；电子顺磁共振（EPR）成像；磁共振成像（MRI）和功能性MRI（fMRI）方法和设备；磁共振弹性图（MRE）成像；超声成像；正电子发射断层扫描（PET）成像；红外荧光成像；语音获取和实时自适应处理；小鼠疼痛模型；和鼻腔腔声表征。这些SPIS能力和成就已确立了该小组作为NIH电气工程研发的焦点。本节的研究和开发活动是与NIH Institute科学家的合作努力，并且经常导致开发独特的专业生物医学工具。其他项目涉及系统模拟和信号分析所需的信号处理算法开发。部分目标是高级模拟和数字电路，生物物理信号转导技术，射频和遥测系统，数字信号处理硬件和软件，可编程逻辑设备，印刷电路电路板的开发，基于光电电机的开发以及基于计算机的信号处理和控制的计算机仪器。