Emotional-Processing in Borderline Personality Disorder

边缘性人格障碍的情绪处理

• 批准号: 7115277
• 负责人: BRETT T LITZ
• 金额: $ 16.48万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-20 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7115277
• 关键词: angers; arousal; behavioral /social science research tag; borderline personality disorder; clinical research; electromyography; emotional adjustment; emotions; face expression; galvanic skin response; heart rate; human subject; impulsive behavior; interpersonal relations; patient oriented research; psychological stressor; psychopathology; psychophysiology; visual stimulus

DESCRIPTION (provided by applicant): The DSM-IV criteria of intense anger and affective instability explicitly underscore emotional-processing abnormalities in BPD, while others (such as frantic efforts to avoid abandonment, repeated suicide attempts or gestures, intense and unstable relationships) may be viewed as strategies to cope with or consequences of this core deficit. Despite the centrality of emotional reactivity to the concept of BPD, surprisingly little research has directly examined emotions in individuals with BPD. An exception is the recent investigation of physiological indicators of emotional reactions to standardized images with pleasant, neutral, or unpleasant emotional valence. In these studies, subjects with BPD did not show more intense responses to any of the stimulus categories, failing to support emotional hyper-responsiveness in BPD. In this proposal, we argue that patients with BPD will show emotional hyper-reactivity after being provoked or triggered by a salient interpersonal challenge. The resultant anger, characterized by high arousal and cognitive and behavioral disinhibition will alter appraisal of emotional cues and interfere with otherwise intact emotional capabilities. The primary aim of this proposal is to conduct the necessary developmental work to examine the emotional-processing consequences of exposure to a personally relevant challenge in BPD. We propose to generate ideographic scripts of recent perceived violation experiences from open-ended semi-structured narrative accounts and examine emotional behavior in the laboratory psychophysiologically (facial EMG, heart rate, and skin conductance response) prior and subsequent to the ideographic challenge. A second aim is to develop sets of emotionally evocative stimuli that are consistent with interpersonal schemas hypothesized to be relevant to BPD, which can be used in future research. A panel of expert BPD clinical researchers will select these sets through a standardized, computer-based sorting procedure. A third aim is to provide a graduate student sufficient knowledge and expertise to conduct independent research in emotional-processing in psychopathology, especially personality disorders. To support these aims, we propose to recruit participants from the ongoing Collaborative Longitudinal Study of Personality Disorders (CLPS) and to examine emotional-processing at the psychophysiological laboratory at the National Center for PTSD in Boston.

描述（由申请人提供）：强烈的愤怒和情感不稳定的DSM-IV标准明确强调了BPD中的情感处理异常，而其他人（例如，避免放弃，反复的自杀企图或手势，强烈的和不稳定的关系和不稳定的关系的狂热努力）可能被视为与此策略相关联的策略，以此为核心范围。尽管情绪反应对BPD的概念具有中心地位，但令人惊讶的是，很少有研究直接研究了BPD患者的情绪。一个例外是对具有令人愉悦，中性或不愉快情绪价值的标准化图像的情绪反应的生理指标的研究。在这些研究中，具有BPD的受试者对任何刺激类别都没有显示更激烈的反应，因此无法支持BPD中的情绪高反应性。在此提案中，我们认为BPD患者在受到显着的人际挑战引起或触发后会表现出情绪高反应性。以高唤醒和认知和行为抑制为特征的最终愤怒将改变对情感提示的评估，并干扰原本完整的情感能力。该提案的主要目的是进行必要的发展工作，以研究BPD中暴露于个人相关挑战的情感处理后果。我们建议从开放式的半结构叙事叙述中产生近期感知到的违规经历的意识形态脚本，并检查实验室心理生理学（面部EMG，心率和皮肤电导反应）的情感行为。第二个目的是开发一组情感令人回味的刺激，这些刺激与假定与BPD相关的人际互块一致，该模式可用于BPD。由专家BPD临床研究人员组成的小组将通过标准化的基于计算机的分类程序选择这些集合。第三个目的是为研究生提供足够的知识和专业知识，以在心理病理学（尤其是人格障碍）方面进行情感处理方面进行独立的研究。为了支持这些目标，我们建议从正在进行的人格障碍纵向研究（CLP）中招募参与者，并在波士顿国家PTSD的心理生理实验室中检查情感处理。

项目成果

Development of a borderline personality disorder-relevant picture stimulus set.

开发与边缘性人格障碍相关的图片刺激集。

• DOI: 10.1521/pedi.2010.24.5.664
• 发表时间: 2010
• 期刊: Journal of personality disorders
• 影响因子: 2.3
• 作者: Sloan,DeniseM;Sege,ChristopherT;McSweeney,LaurenB;Suvak,MichaelK;Shea,MTracie;Litz,BrettT
• 通讯作者: Litz,BrettT