CAP-Assessment Core Boston

CAP-评估核心波士顿

• 批准号: 8827165
• 负责人: BRETT T LITZ
• 金额: --
• 依托单位: VA BOSTON HEALTH CARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8827165
• 关键词: Acute; Address; Alcohol or Other Drugs use; Behavioral; Biological; Biological Markers; Boston; Characteristics; Chronic; Clinical Trials; Cognitive; Common Data Element; Conduct Clinical Trials; Data; Data Set; Detection; Development; Diagnosis; Diagnostic; Dictionary; Ensure; Environmental Exposure; Epidemiologic Studies; Epidemiology; Etiology; Evaluation; Exposure to; Funding; Future; Genetic; Genomics; Goals; Headache; Individual Differences; Institute of Medicine (U.S.); Institutes; Institution; Interest Group; International; Interview; Life Cycle Stages; Measurement; Measures; Medical; Medical center; Mental Depression; Mental Health; Military Personnel; Modeling; NIH Program Announcements; Needs Assessment; Neurobiology; Outcome; Pain; Patients; Personal Satisfaction; Plant Roots; Population; Post-Traumatic Stress Disorders; Prevention; Prevention strategy; Preventive; Procedures; Property; Proteomics; Psychometrics; Publishing; Randomized Clinical Trials; Rehabilitation therapy; Reporting; Research; Research Infrastructure; Research Personnel; Risk; Services; Shapes; Site; Sleep disturbances; South Carolina; Stress; Suicide; Supervision; Systems Biology; Time; Training; Trauma; Treatment outcome; United States National Institutes of Health; Universities; Veterans; War; Work; adjudicate; base; behavioral health; combat; effective intervention; experience; improved; instrumentation; member; multidisciplinary; neuroimaging; novel; outcome forecast; physical conditioning; post-traumatic stress; preclinical study; prevent; prognostic; psychologic; resilience; sound; success; treatment response

The Assessment Core has four main objectives that support proposed and future clinical trials and epidemiological studies: (1) to create uniformity of instrumentation and measurement and to employ state-of- the-art measures with sound psychometric properties; (2) to ensure measurement of outcome and predictor variables that are relevant and sensitive to the active duty military ethos and culture as well as Veterans' experiences; (3) to train and to provide oversight and supervision of Independent Evaluators (IEs), to adjudicate diagnostic decisions for clinical trials when necessary, to conduct inter-rater reliability evaluations of taped PTSD interviews, and to shape IEs over time to obviate drift; and (4) to work with the Data and Epidemiological Cores to create a data dictionary and to manage and leverage the omnibus multi-study dataset. Our team has specialized expertise in the assessment of war-trauma (Litz, 2007; Litz & Schlenger, 2009; Steenkamp et al., 2010; Stein et al., 2012) and has extensive experience measuring risk and resilience in the military over the life-course (Baker et al., 2012; Dickstein et al., 2010). The infrastructure created under STRONG STAR is well-equipped to effectively oversee the measurement and assessment needs for STRONG STAR-CAP. To date, we have selected outcome and predictor variables that are state-of-the-art and that provide content coverage across multiple domains while respecting Service Members' and Veterans time-and- effort constraints. We were especially mindful of the latter and chose briefer options whenever possible. Ronald Acierno at the Charleston VA Medical Center/Medical University South Carolina has organized an informal research Consortium consisting of approximately 10 non-NCPTSD investigators located at VAs throughout the US (see Table 5) who are committed to partnering with the Assessment Core and the STRONG STAR-CAP. All of the investigators have current VA, DoD, or NIH funding to support their PTSD research. A primary interest of this group is to help ensure that a set of Common Data Elements (Kaloupek et al., 2010) are collected across all DoD and VA STRONG STAR-CAP-affiliated studies (e.g., common psychological construct domains, biomarkers, etc.). They have titled their effort the Coalition of VA/DoD PTSD CAP Study Site Partners for Common Data Elements.

评估核心有四个主要目标，这些目标支持拟议的和未来的临床试验，以及 流行病学研究：（1）建立仪器和测量的统一性，并采用最终 具有声音心理测量特性的措施； （2）确保测量结果和预测因子 与现役军事精神和文化以及退伍军人相关且敏感的变量 经验； （3）培训并提供对独立评估者（IES）的监督和监督， 在必要时裁定临床试验的诊断决策，进行评估间的可靠性评估 随着时间的流逝，胶带PTSD采访，并塑造出IES以消除漂移； （4）与数据一起工作 流行病学核心创建数据词典，并管理和利用综合多学生数据集。 我们的团队在评估War-Trauma方面拥有专业知识（Litz，2007； Litz＆Schlenger，2009年； Steenkamp等人，2010年； Stein等，2012），并具有丰富的经验，可衡量风险和韧性 在生命过程中的军事（Baker等，2012； Dickstein等，2010）。在下面创建的基础架构 Strong Star具有良好的能力，可以有效监督强大的测量和评估需求 星帽。迄今为止，我们选择了最先进的结果和预测变量， 在尊重服务成员和退伍军人的同时提供跨多个领域的内容覆盖范围 努力限制。我们特别注意后者，并尽可能选择Briefer选择。罗纳德 查尔斯顿弗吉尼亚州医学中心/医科大学南卡罗来纳州的Acierno组织了非正式 研究财团由位于VAS的大约10位非NCPTSD研究人员组成 美国（请参阅表5）致力于与评估核心和强大的恒星帽合作。全部 研究人员目前拥有VA，DOD或NIH资金来支持其PTSD研究。主要兴趣 该组的旨在帮助确保一组共同的数据元素（Kaloupek等，2010） 所有DOD和VA强的Star-Cap相关研究（例如，常见的心理结构领域， 生物标志物等）。他们的努力为VA/DOD PTSD CAP研究站点合作伙伴的努力 常见数据元素。