Internet-Based Cancer Symptom Management: WRITE Symptoms

基于互联网的癌症症状管理：WRITE Symptoms

• 批准号: 7140019
• 负责人: Heidi S Donovan
• 金额: $ 17.95万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-15 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7140019
• 关键词: Internet; behavioral /social science research tag; cancer complication; clinical research; computer assisted instruction; computer assisted medical decision making; computer assisted patient care; data collection methodology /evaluation; female; functional ability; health care service evaluation; health care service planning; health services research tag; human subject; human therapy evaluation; neoplasm /cancer education; ovary neoplasms; patient care management; quality of life; self care; sign /symptom; therapy design /development; women' s health

DESCRIPTION (provided by applicant): Many individuals with cancer experience multiple, co-occurring symptoms that drastically impair functioning and quality of life. The process of trying to manage multiple symptoms can be overwhelming to patients. An innovative approach to patient education has recently been developed that should facilitate the process of managing multiple symptoms9. This proposal represents the first phase in the process of applying the representational approach to a new delivery mode (from in-person interviews to correspondence via secure internet messaging services) and to a more complex patient care situation (from management of a single, pre-determined symptom to multiple, patient-selected symptoms). We refer to this as a Written Representational intervention To Ease Symptoms, or WRITE symptoms. The specific aims of this pilot study, conducted in collaboration with the National Ovarian Cancer Coalition (NOCC), are to conduct preliminary evaluations (feasibility, acceptability, and initial efficacy) of WRITE symptoms with a sample of women with recurrent ovarian cancer. Subjects will be 90 women experiencing two or more bothersome symptoms associated with ovarian cancer recruited via mailed invitations and advertisements on the NOCC website. Women will be randomly assigned to one of 2 conditions: 1) a full baseline assessment, WRITE symptoms intervention group; and 2) a full baseline assessment, modified wait-list control group. WRITE symptoms will be delivered via secure messaging services situated on the NOCC website. Measures of symptom representations, symptom interference with life activities and quality of life will be completed by all subjects at baseline and 5 and 9 weeks later. Assessment of feasibility and acceptability will be conducted during recruitment, throughout the study period, and after subjects have completed the study. Should WRITE symptoms pass initial evaluations of feasibility, acceptability, and efficacy, knowledge gained from this pilot study will be used to plan a randomized controlled trial grant application (R01) to determine the efficacy of the intervention and the potential mechanism(s) through which the intervention has its effect.

描述（由申请人提供）：许多患有癌症的人会经历多种，同时发生的症状，这些症状会严重损害功能和生活质量。试图管理多种症状的过程对患者来说可能是压倒性的。最近已经开发了一种创新的患者教育方法，该方法应促进管理多种症状的过程9。该提案代表了将代表性方法应用于新的分娩模式（从面对面的访谈到通过安全的Internet消息传递服务的通信）和更复杂的患者护理状况（从单一预先确定的症状的管理到多种，患者选择的症状）的第一阶段。我们将其称为书面代表性干预措施，以减轻症状或写症状。 该试点研究的具体目的是与国家卵巢癌联盟（NOCC）合作进行的，是针对与复发性卵巢癌的女性样本进行写症状的初步评估（可行性，可接受性和初始疗效）。受试者将是90名女性，经历了两种或多种麻烦的症状，与NOCC网站上的邮寄邀请函和广告招募有关的卵巢癌症状。妇女将被随机分配到2个条件之一：1）完整的基线评估，写症状干预组； 2）完整的基线评估，修改的等待名单对照组。写症状将通过位于NOCC网站上的安全消息服务提供。症状表示的度量，症状干扰生活活动和生活质量将由基线和5周后的所有受试者完成。在招聘期间，整个研究期间以及受试者完成研究后，将对可行性和可接受性进行评估。应写症状通过对可行性，可接受性和疗效的初步评估，该试点研究获得的知识将用于计划随机对照试验授予申请（R01），以确定干预措施的疗效以及干预措施具有其作用的潜在机制。