Accelerated discovery and development of functionalised block copolymers using continuous-flow anionic polymerisation platforms

使用连续流阴离子聚合平台加速功能化嵌段共聚物的发现和开发

基本信息

批准号：
2665495
负责人：
金额：
--
依托单位：
University of Leeds
依托单位国家：
英国
项目类别：
Studentship
财政年份：
2021
资助国家：
英国
起止时间：
2021 至无数据
项目状态：
未结题

来源：
https://gtr.ukri.org/projects?ref=studentship-2665495
关键词：
Accelerated discovery development functionalised block

项目摘要

Anionic polymerisation is an industrially established method of synthesising polymers with defined molecular weights and architectures. This includes the formation of block copolymers, which form advanced nanomaterials with highly desirable properties. Unfortunately, anionic polymerisation for the formation of block copolymers is a synthetically challenging process meaning it is difficult to conduct efficient optimization of parameters and product composition. Streamlining this overall process would therefore be highly desirable both industrially and academically since it could provide affordable new advanced and sustainable polymers. This project aims to develop new and user friendly techniques for high-throughput, rapid proto-typing and optimisation of anionic copolymerisation and polymer functionalization. The experimental approach will involve adapting continuous-flow reactors equipped with online monitoring and computational control interfaces to the anionic polymerisation process. These reactors would then enable rapid optimization of conditions and prototyping of polymers The student will first be trained in anionic polymerisation at the University of Durham within Prof Lian Hutchings laboratories. They will then move to Leeds where they will work within Dr Nick Warren's laboratories which is part of both the Colloid and Polymer Engineering and Digital Manufacturing and emerging technology groups. Here, they will build reactors which are capable of anionic polymerisation and exploit them for rapid prototyping of polymerisation systems.

阴离子聚合是一种具有定义的分子量和体系结构合成聚合物的工业建立方法。这包括形成块共聚物，该块共聚物形成具有高度理想特性的高级纳米材料。不幸的是，形成块共聚物的阴离子聚合是一个综合挑战的过程，这意味着很难对参数和产品组成进行有效的优化。因此，简化这一整体过程在工业和学术上都是非常可取的，因为它可以提供负担得起的新的高级和可持续的聚合物。该项目旨在开发新的和用户友好的技术，用于高通量，快速的原始型和优化阴离子共聚和聚合物功能化。实验方法将涉及调整配备在线监测和计算控制接口的连续流动反应器，以适应阴离子聚合过程。然后，这些反应堆将能够快速优化条件和聚合物的原型化，该学生将首先在Lian Hutchings实验室内的达勒姆大学接受Durham大学的阴离子聚合培训。然后，他们将搬到利兹，在那里他们将在尼克·沃伦（Nick Warren）博士的实验室中工作，这是胶体和聚合物工程以及数字制造和新兴技术组的一部分。在这里，它们将构建能够具有阴离子聚合的反应器，并利用它们来快速原型聚合系统。