Alcohol, Mortality and Ethnicity in the US

美国的酒精、死亡率和种族

• 批准号: 7217154
• 负责人: Carlos J. Crespo
• 金额: $ 19.95万
• 依托单位: PORTLAND STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7217154
• 关键词: African American; American; Hispanic Americans; United States; age difference; alcoholic beverage consumption; alcoholism /alcohol abuse; atherosclerosis; coronary disorder; epidemiology; high risk behavior /lifestyle; human data; human middle age (35-64); human mortality; human old age (65+); injury; mathematical model; neoplasm /cancer; racial /ethnic difference; substance abuse related behavior; young adult human (21-34)

DESCRIPTION (provided by applicant): Interview Survey (NHIS) offer a unique chance to explore the relationships between different dimensions of alcohol consumption with all-causes & cause-specific mortality in different ethnic groups in the US. The following specific hypotheses will be tested: HI: Overall, there will be a J-shaped curve between average volume of alcohol consumption & all-cause mortality in people over 45 years of age, & a linear curve in younger persons. H2: A drinking pattern with heavy drinking occasions will confer no beneficial effects on all-causes mortality. H3-4: The relationships between average volume of alcohol consumption & all-causes mortality will be specific to ethnicity, based on the respective drinking patterns. H5-7: As heavy drinking occasions are relevant for Coronary Heart Disease & injuries, the cause specific mortality for those causes of death with be ethnic group specific, whereas for cancers no such interaction between average volume of alcohol consumption and ethnicity is expected. The NHIS is a representative cross-sectional survey of the civilian, non-institutionalized US population. For the1988 & 1990 NHIS, marital status & underlying cause of death are available for all adults18 years & older with follow-up through 12/31/97. The baseline sample will include 81,464 men (n=33,989) & women (47,475) with 5,585 Hispanic men (n=2,303) & women (3,282) & 11,253 non-Hispanic Black men (n=3,983) & women (7,270). The approx. 8 years of follow-up will include a total of 8,294 deaths, 302 Hispanic deaths and 1,223 deaths in non-Hispanic Blacks. This will be the largest representative US sample to date used to investigate the association between dimensions of alcohol intake & mortality in the major US minority groups. Proportional hazard regression models will be used on the combined data, once homogeneity of samples is established. The results will provide important background data for shaping ethnicity-specific preventive measures for avoiding alcohol-related burden of disease.

描述（由申请人提供）：访谈调查（NHIS）提供了一个独特的机会，可以探索美国不同族裔群体中不同族裔和特定原因死亡率之间不同饮酒量之间的关系。将测试以下特定假设：HI：总体而言，45岁以上的人的平均饮酒量与全因死亡率之间的J形曲线与年轻人的线性曲线之间的曲线。 H2：饮酒方式与大量饮酒场合会赋予对所有原因死亡的有益影响。 H3-4：基于各自的饮酒方式，平均饮酒量与全法死亡率之间的关系特定于种族。 H5-7：由于大量饮酒场合与冠心病和伤害有关，因此特定于族裔的死亡原因的特定原因是特定的，而对于癌症而言，预计平均饮酒量与种族之间没有这种相互作用。 NHIS是对民用，非机构化的美国人口的代表性横断面调查。对于1988年和1990年的NHIS，婚姻状况和潜在的死因可为所有成年人18岁以上，随访至12/31/97。基线样本将包括81,464名男性（n = 33,989）和女性（47,475），其中包括5,585名西班牙裔男性（n = 2,303）和妇女（3,282）和11,253个非西班牙裔黑人男人（n = 3,983）和女性（7,270）。大约8年的随访将包括8,294人死亡，302例西班牙裔死亡和非西班牙裔黑人死亡1,223人死亡。迄今为止，这将是美国主要少数群体中酒精摄入量与死亡率之间的关联的最大代表性样本。一旦建立了样品的均匀性，将使用比例危害回归模型。结果将为塑造特定于种族的预防措施提供重要的背景数据，以避免与酒精相关的疾病负担。