Molecular Biology of Intestinal Lipid Transport /Metabol

肠道脂质运输/代谢的分子生物学

• 批准号: 7161884
• 负责人: SHAILENDRA BHANUBHAI PATEL
• 金额: $ 1.2万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-20 至 2007-07-19
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7161884
• 关键词: gastrointestinal system; lipid transport; meeting /conference /symposium; metabolism; molecular biology; travel

DESCRIPTION (provided by applicant): The FASEB Summer Conference on the Molecular Biology of Lipid Transport and Metabolism will bring together scientists in a variety of related fields with the purpose of defining, describing and analyzing critical scientific problems and recent advances in an intimate and interactive environment. A key feature of this meeting is the opportunity to facilitate the interactions of students and postdoctoral fellows with senior established figures in the field. Such interactions have historically been successful in defining new research agendas and fostering scientific discourse and collaborations. This application requests partial funding for a Conference to be held July 15 to 20, 2006 at the Omni Resort in Tucson, Arizona. This will be the sixth such conference on this theme; the last one was held in the summer of 2003. This conference is unique in its highly multidisciplinary approach to study a key problem of mammalian physiology. Thus, we will bring together a diverse group of senior and junior investigators with expertise in the areas of nutrition, physiology, biochemistry, protein chemistry, cell and molecular biology, and developmental biology, to address recent advances in lipid metabolism and its regulation. The format will consist of seven major oral sessions scheduled over four days (four AM and three PM), an evening Keynote Address and two poster sessions. To date 26 highly noteworthy invited speakers have confirmed their willingness to participate. The seven formal sessions focus on active research areas: 1) Intestinal Sterol Trafficking; 2) Lipid Transport and Bile acid Metabolism; 3) Dietary Lipids in Extra-hepatic Tissues; 4) Fat Metabolism in Model Organisms; 5) Lipid Disorders with Multi-organ effects; 6) Nuclear Receptors with Lipid Ligands; and 7) Cell biology and Genetics of Lipid Metabolism. The ultimate session will be a key note address from Jeffrey Gordon on Intrinsic and extrinsic regulators of intestinal lipid metabolism. All participants will be invited to submit an abstract to one of two poster sessions that will be held during the conference in order to allow all attendees, especially students and junior investigators to present data and participate in discussions. Additional speakers will be chosen from the abstract submissions, and all participants will be encouraged to submit particularly novel late-breaking developments for brief oral presentation in the form of "hot topics". These hot topics sessions will be targeted specifically to accommodate junior scientists. In the past this conference has promoted interactions and scientific discussions among basic and clinical investigators from academia and industry. The limited attendance, state of the art scientific sessions, "hot topics" additions, and novel poster presentations combine to provide an essential forumthat will foster exchange of ideas and further scientific advances in a field where advances in basic research have historically been directly translated into improved therapeutic options for a large fraction of the population.

描述（由申请人提供）： FASEB 脂质运输和代谢分子生物学夏季会议将带来 将各个相关领域的科学家聚集在一起，目的是定义、描述和分析 在亲密互动的环境中关键的科学问题和最新进展。这次会议的一个主要特点是有机会促进学生和博士后研究员与该领域资深人士的互动。历史上，这种互动在确定新的研究议程和促进科学讨论与合作方面取得了成功。该申请要求为 2006 年 7 月 15 日至 20 日在亚利桑那州图森 Omni 度假村举行的会议提供部分资金。这将是关于这一主题的第六次此类会议；上一次会议于 2003 年夏天举行。这次会议的独特之处在于它采用高度跨学科的方法来研究哺乳动物生理学的一个关键问题。因此，我们将汇集营养、生理学、生物化学、蛋白质化学、细胞和分子生物学以及发育生物学领域专业知识的多元化高级和初级研究人员，以解决脂质代谢及其调节的最新进展。该形式将包括七场主要口头会议，安排在四天内（上午四点和下午三点）、晚间主题演讲和两场海报会议。迄今为止，已有 26 位备受关注的受邀演讲嘉宾确认愿意参加。七个正式会议重点关注活跃的研究领域：1）肠道甾醇贩运； 2）脂质运输和胆汁酸代谢； 3）肝外组织中的膳食脂质； 4）模型生物体的脂肪代谢； 5）具有多器官效应的脂质紊乱； 6) 具有脂质配体的核受体； 7) 细胞生物学和脂质代谢遗传学。最终会议将由 Jeffrey Gordon 发表关于肠道脂质代谢的内在和外在调节剂的主题演讲。所有参与者将被邀请向会议期间举行的两次海报会议之一提交摘要，以便所有与会者，特别是学生和初级研究人员能够展示数据并参与讨论。其他演讲者将从提交的摘要中选出，并鼓励所有参与者提交特别新颖的最新进展，以“热点话题”的形式进行简短的口头演讲。这些热门话题会议将专门针对年轻科学家。过去，该会议促进了学术界和工业界基础和临床研究人员之间的互动和科学讨论。有限的出席人数、最先进的科学会议、“热门话题”的补充和新颖的海报展示相结合，提供了一个重要的论坛，将促进基础研究的进步在历史上直接转化为领域的思想交流和进一步的科学进步。为很大一部分人口提供了改善的治疗选择。