Conference Modeling of Protein Interactions in Genomes

基因组中蛋白质相互作用的会议建模

• 批准号: 7000500
• 负责人: SANDOR VAJDA
• 金额: $ 0.5万
• 依托单位: BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-15 至 2006-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7000500
• 关键词: genome; meeting /conference /symposium; protein protein interaction; protein structure; travel

DESCRIPTION (provided by applicant): Support is requested for the multidisciplinary conference MODELING OF PROTEIN INTERACTIONS IN GENOMES 2005, to be held on 24-27 June, 2005 in Lawrence, Kansas. The meeting will involve a combination of biological, physical, and computational scientists, and will focus on computational procedures for reconstruction and study of the networks of connections between proteins in genomes, including experimental studies, knowledge-based methods, sequence analysis, and structural approaches. The specific aims of the Modeling of Protein Interactions in Genomes Conference 2005 are as follows: (1) discussion of the structural aspects of protein interactions, including docking methods; (2) discussion of current and emerging methods of determining protein binding sites using both sequence-based and structure-based approaches; (3) modeling of protein-protein interactions on the basis of a diverse set of experimental techniques (e.g., mass spectroscopy, cryo-electron microscopy, cross-linking, NMR, etc); and (4) solving computational problems associated with the analysis of protein interaction networks from large-scale screening experiments (primarily two-hybrid essays and mass spectrometry). Experts from various areas of protein interactions were selected to serve on our Advisory Committee and also to present at the conference. Further presentations will be invited as well as selected by the Advisory Committee from the submitted abstracts. A poster session will be held on one of the conference days. The conference will be relatively small - approximately 100 participants. The organizers will pay special attention to attracting young investigators as speakers and poster presenters. We will encourage participation of students and postdoctoral fellows. An important aspect of the conference organization will be our effort to diversify the participation by attracting women and minority scientists. This will primarily achieved by contacting faculty members working in the areas of Biophysics and Biochemistry in minority-serving institutions.

说明（由申请人提供）：请求支持将于 2005 年 6 月 24-27 日在堪萨斯州劳伦斯举行的 2005 年基因组中蛋白质相互作用建模多学科会议。会议将由生物、物理和计算科学家共同参与，重点讨论用于重建和研究基因组中蛋白质之间连接网络的计算程序，包括实验研究、基于知识的方法、序列分析和结构方法。 2005年基因组蛋白质相互作用建模会议的具体目标如下：（1）讨论蛋白质相互作用的结构方面，包括对接方法； (2) 讨论使用基于序列和基于结构的方法确定蛋白质结合位点的当前和新兴方法； (3) 基于多种实验技术（例如质谱、冷冻电子显微镜、交联、核磁共振等）对蛋白质-蛋白质相互作用进行建模； （4）解决与大规模筛选实验（主要是双杂交论文和质谱）中蛋白质相互作用网络分析相关的计算问题。 来自蛋白质相互作用各个领域的专家被选为我们的顾问委员会成员并出席会议。咨询委员会将邀请并从提交的摘要中选择进一步的演讲。海报会议将在会议日之一举行。会议规模相对较小——大约有 100 名与会者。组织者将特别注重吸引年轻研究者作为演讲者和海报展示者。我们将鼓励学生和博士后的参与。会议组织的一个重要方面是我们通过吸引女性和少数族裔科学家来努力实现参与多元化。这主要通过联系少数族裔服务机构中生物物理学和生物化学领域的教职人员来实现。