Neuroscience and Health Annex on the Coral Gables Campus at the University of Mia

米亚大学科勒尔盖布尔斯校区的神经科学与健康附楼

• 批准号: 7874377
• 负责人: Leonidas G Bachas
• 金额: $ 1482.16万
• 依托单位: UNIVERSITY OF MIAMI CORAL GABLES
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-02-01 至 2013-11-18
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7874377
• 关键词: American; Animals; Arts; Behavior; Behavioral; Behavioral Medicine; Biological; Biological Models; Brain; Brain imaging; Brain region; Certification; Commit; Complex; Functional Magnetic Resonance Imaging; Funding; Goals; Health; Health Psychology; Housing; Human; Image; Image Analysis; In Situ; Interdisciplinary Study; Laboratories; Lead; Leadership; Molecular; Natural regeneration; Nervous system structure; Neurosciences; Occupations; Pattern; Research; Research Personnel; Resources; Science; Silver; Spinal cord damage; Study models; System; Universities; base; brain behavior; coral; design; frontier; laboratory facility; molecular imaging; nervous system disorder; programs; public health relevance; relating to nervous system; square foot

DESCRIPTION (provided by applicant): To promote effective transformational collaborative research in state-of-the art laboratory facilities, we propose to build a 37,700 sq ft addition (Neuroscience and Health Annex) to the Cox Science Building on the Coral Gables campus at the University of Miami. The Neuroscience and Health Annex will create an interactive "hub" for researchers on the interdisciplinary research theme of Brain, Behavior and Health in studies requiring sophisticated image analysis. The planned Neuroscience and Health Annex comprises multiple interlinked foci based on biological imaging and health research. There are senior NIH-funded investigators in each of the research foci (e.g., Chiba/Advanced Molecular Imaging, Schneiderman/Health Psychology/ Behavioral Medicine Research, Sacco and Maudsley/fMRI Brain Imaging). These foci are supported by a system of collaborative research spaces designed to house resources needed for multiple research endeavors. The annex will provide facilities for a fMRI core laboratory, an advanced in situ molecular imaging complex and a vivarium. It will consolidate behavioral researchers and will bring them into close contact with one another and with other neuroscientists in space specifically designed for their research needs. The annex will be designed and built following US Green Building Council sustainable design criteria with the goal of achieving LEED Silver Certification. The University is committed to providing funds to complete the project and to purchase a fMRI magnet. Funding of this project is expected to generate 189 American jobs (174 industrial and 15 academic) and has full support of the university leadership. PUBLIC HEALTH RELEVANCE (provided by the applicant): The great frontier for neuroscience is to understand how molecular changes in the nervous system relate to behavior and to identify different molecular patterns in the nervous system that can predict successful treatment of neurological diseases and in some cases lead to successful regeneration of damaged spinal cord or brain. The research programs in the Neuroscience and Health Annex will contribute to this effort by studying model systems in animals and correlate human behavior with functional changes in different regions of the brain.

描述（由申请人提供）：为了在最先进的实验室设施中促进有效的变革性协作研究，我们建议在迈阿密大学的Coral Gables校园内建立37,700平方英尺的添加（神经科学和健康附件）。神经科学和健康附件将为研究人员创建一个互动的“枢纽”，涉及大脑跨学科研究主题，行为和健康的主题，在需要复杂的图像分析的研究中。计划的神经科学和健康附件包括基于生物成像和健康研究的多个相互关联的焦点。 NIH资助的每个研究灶都有高级资助的研究人员（例如，千叶/高级分子成像，Schneiderman/health心理学/行为医学研究，Sacco和Maudsley/fMRI脑成像）。这些焦点得到了一个协作研究空间系统的支持，旨在容纳多项研究所需的资源。该附件将为fMRI核心实验室，一个先进的原位分子成像复合物和Vivarium提供设施。它将巩固行为研究人员，并将他们与彼此之间以及专门针对其研究需求设计的空间中的其他神经科学家保持密切联系。该附件将在美国绿色建筑委员会可持续设计标准之后进行设计和建造，以实现LEED银认证。该大学致力于提供资金来完成该项目并购买fMRI磁铁。该项目的资金预计将产生189个美国工作（174个工业和15个学术），并全力支持大学领导。 公共卫生相关性（由申请人提供）：神经科学的重要领域是了解神经系统中的分子变化与行为的变化如何与神经系统中的不同分子模式有关，以预测神经系统疾病的成功治疗，并在某些情况下导致成功地重新恢复受损脊髓或大脑的神经系统疾病。神经科学和健康附件中的研究计划将通过研究动物的模型系统并将人类行为与大脑不同区域的功能变化相关联，从而为这一努力做出贡献。