Stanford - South Africa Biomedical Informatics Program

斯坦福大学-南非生物医学信息学项目

• 批准号: 6918727
• 负责人: RUSS BIAGIO ALTMAN
• 金额: $ 25万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-06-01 至 2007-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6918727
• 关键词: AIDS therapy; Africa; bioinformatics; biomedical registry /referral center; curriculum; education evaluation /planning; educational resource design /development; genetic registry /resource /referral center; health science research potential; human immunodeficiency virus; international cooperation; microorganism resource /registry; patient /disease registry; training; university; virus genetics; AIDS therapy; Africa; bioinformatics; biomedical registry /referral center; curriculum; education evaluation /planning; educational resource design /development; genetic registry /resource /referral center; health science research potential; human immunodeficiency virus; international cooperation; microorganism resource /registry; patient /disease registry; training; university; virus genetics

DESCRIPTION (provided by applicant): Recent highly publicized disease outbreaks illustrate the need to increase the capacity of the biomedical community to collect, manage and rapidly exchange data that spans basic biology and medicine worldwide. As part of a global strategy to combat epidemics, such as human immunodeficiency virus (HIV), there is an unfulfilled need to develop and support the capacity to train effective, ethical biomedical informatics researchers in the countries most affected. Our proposal addresses this need by leveraging the recently established, bioinformatics training program at the University of the Western Cape (UWC), South Africa to revolve towards a Biomedical Informatics program and responds directly to the acute shortage of trained faculty in South Africa. A focused development program will enable experience gained through the long established Biomedical Informatics program at Stanford University to contribute significantly and sustainable towards shortcomings that have been identified by the existing faculty at UWC. This proposal focuses on developing new trainers by three mechanisms: 1) Extend the graduate curriculum with jointly developed and taught short courses from Stanford, 2) develop local teaching talent with support for trainees at UWC, and 3) enrich the research community and develop new curricular matedal in biomedical informatics by supporting Visiting Scholars and students from UWC at Stanford University. High priority projects supported by this program include development of a South African National HIV Database that builds upon an existing NIH funded initiative at UWC to serve the needs of genomicists, epidemiologists and the health care community. Information about HIV genomic variations and patient responses to various antiviral therapies will be collected and new or improved treatments developed as a result. The need for such a database to support the NIH-funded Caprisa project has previously been identified and initial support has been gained through the NIH-funded CAPRISA program (www.caprisa.org).

描述（由申请人提供）：最近的高度宣传疾病暴发说明了增加生物医学界收集，管理和迅速交换涵盖全球基本生物学和医学的数据的必要性。 作为对抗流行病的全球战略的一部分，例如人类免疫缺陷病毒（HIV），在最受影响最受影响的国家中培训有效的，道德的生物医学信息学研究人员的能力是不满足的。我们的建议通过利用西开普大学（UWC）的最近建立的生物信息学培训计划来解决这一需求，南非朝着生物医学信息学计划发展，并直接应对南非训练有素的教师的严重短缺。一项重点发展计划将使斯坦福大学长期建立的生物医学信息学计划获得的经验能够为UWC现有教师所确定的缺点做出重大和可持续的贡献。该建议的重点是通过三种机制开发新培训师：1）通过共同开发和教授斯坦福大学的简短课程，2）在UWC的支持下，开发本地教学人才，并在UWC的支持下进行支持，3）丰富研究社区，并通过支持访问Biomedical Scholarars和Stanfords Standerforce nivils Stanford Commess Stanford Commesss Stanford Comments Stanford Commentical of Biomedical Mational in New Currical Mational Matisal Mational of BioMedical Mastilal。该计划支持的高优先级项目包括开发南非国家艾滋病毒数据库，该数据库基于UWC现有的NIH资助计划，以满足基因组学家的需求， 流行病学家和卫生保健社区。将收集有关HIV基因组变异和患者对各种抗病毒疗法的反应的信息，并因此而开发新的或改进的治疗方法。以前已经确定了这样的数据库来支持NIH资助的CAPRISA项目，并通过NIH资助的CAPRISA计划（www.caprisa.org）获得了初始支持。