Family-Centered Diabetes Project

以家庭为中心的糖尿病项目

• 批准号: 6885740
• 负责人: Carla Jean Herman
• 金额: $ 4.38万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-08-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6885740
• 关键词: Native Americans; behavioral /social science research tag; blood tests; body composition; body physical activity; body weight; diabetes education; disease /disorder prevention /control; disease /disorder proneness /risk; education evaluation /planning; family; female; health care service utilization; human subject; insulin sensitivity /resistance; nutrient intake activity; nutrition; nutrition related tag; patient oriented research; physical fitness; questionnaires; role model; women' s health; young adult human (21-34)

Diabetes is a major health problem among Native American (NA) communities nationally and in New Mexico. Diabetes prevention efforts should concentrate on modifiable risk factors. Young NA women are important recipients of diabetes prevention activities because of their pivotal role in the family environment as they purchase and prepare food, and care for their children and families. They are also important recipients of diabetes prevention because of their own high risk of diabetes. Therefore, the long-range goal of this study is to reduce modifiable diabetes risk factors in NA women and their families through a culturally specific intervention. The specific aim of this study is to determine whether a healthful lifestyle intervention program, "Sharing Wisdom", delivered to young NA women without diabetes will reduce diabetes risk factors. A randomized trial design will be used with two experimental groups: intervention group, and comparison group who will receive a delayed intervention. Measures will be completed at the General Clinical Research Center (GCRC) with assistance from the research team at baseline, post intervention, and 6 and 12 months post intervention. Process evaluation will be conducted by a separate team. The target population is NA women ages 18-40 who attend the Indian Health Service (IHS) clinics or an urban Indian clinic. The following hypotheses will be tested: i) Intervention participants will attend the Sharing Wisdom program with a greater than or equal to 80 percent retention rate for the intervention and will evaluate the program positively. ii) Intervention participants will have improvement on diabetes risk factors (primary outcomes) when compared to the comparison group post intervention: decreased percent fat from kcal in the diet, increased vegetable consumption measured using the Block Food Frequency Questionnaire, and increased percent of participants who do moderate or strenuous physical activity for 30 minutes greater than 3 times a week using the Modifiable Activity Questionnaire of Kriska. iii) Intervention participants will improve on clinical measures (secondary outcomes) compared to the comparison group post intervention: improved physical fitness measured by predicted VO2 peak, decreased body fat measured by skinfold thickness, decreased body weight, and decreased insulin resistance using the HOMA model. iv) Improvement in outcome measures will be maintained by intervention participants when compared to the comparison group at 6 and 12 months post intervention.

糖尿病是全国和新墨西哥州原住民（NA）社区的主要健康问题。 预防糖尿病的工作应集中于可修改的危险因素。年轻的NA妇女是预防糖尿病活动的重要接受者，因为她们在购买和准备食物时在家庭环境中的关键作用，并照顾孩子和家庭。 由于自身患糖尿病的高风险，它们也是预防糖尿病的重要接受者。因此，这项研究的远距离目标是通过具有文化特定的干预措施来减少NA妇女及其家庭中可修改的糖尿病风险因素。 这项研究的具体目的是确定健康的生活方式干预计划“共享智慧”是否会递给没有糖尿病的年轻妇女，这会减少糖尿病的危险因素。 随机试验设计将与两个实验组一起使用：干预组和将接受延迟干预的比较组。 在基线，干预后以及干预后6个月和12个月的研究小组的协助下，将在一般临床研究中心（GCRC）完成措施。 流程评估将由一个单独的团队进行。 目标人群是参加印度卫生服务（IHS）诊所或印度城市诊所的18-40岁妇女。 将测试以下假设：i）干预参与者将参加干预措施的分享智慧计划，以大于或等于80％的保留率，并将积极评估该计划。 ii）与比较组的干预后相比，干预参与者将改善糖尿病的危险因素（主要结果）：饮食中KCAL的脂肪百分比降低，使用块食品频率问卷来测量的蔬菜消耗量增加，并且使用改进的Activener Activener Qrarka kriSka kriska kribsike kriSka kriska searka seake a Greatife the Ane Ane A MINTER 30分钟的参与者增加了30分钟。 iii）与比较组的干预组相比，干预参与者将改善临床措施（次要结果）：通过预测的VO2峰值测量的身体适应性改善，通过使用HOMA模型来测量的VO2峰值，减少了皮肤折叠厚度，体重降低和胰岛素抵抗的降低。 iv）与在干预后6和12个月的比较组相比，干预参与者将通过干预参与者进行改进。