ASM Conference on Viral Immune Evasion

ASM 病毒免疫逃避会议

• 批准号: 6943804
• 负责人: HERBERT W VIRGIN
• 金额: $ 2万
• 依托单位: AMERICAN SOCIETY FOR MICROBIOLOGY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-01-15 至 2005-12-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6943804
• 关键词: host organism interaction; immune response; meeting /conference /symposium; microorganism immunology; travel; virus infection mechanism

Viral virulence is the result of a number of aspects of virus biology including intrinsic growth rates, transmissibility, cell tropism, and tissue tropism. In addition, viruses face significant hurdles when confronted first by the innate immune response and then by adaptive immunity. In response, viruses have a number of strategies for inhibiting immune activation or for blocking the effectors used by the immune system to combat infection. The contributions of immune evasion have been recognized for many years, but only have been analyzed in mechanistic detail in the past decade. This has led to a significant increase in understanding of viral immune evasion over the past decade. The ASM Conference on Viral Immune Evasion is designed to bring the top researchers in the world on mechanisms of viral immune evasion together to share information in this rapidly advancing area. We have the following specific aims: Specific Aim 1: Create a community of scholars that share an interest in viral immune evasion. As many of the investigators invited to the conference work in different viral systems and therefore do not attend the same meetings, the schedule and speaker selection is designed to create a new grouping of investigators and trainees that share a common interest in viral immune evasion. Specific Aim 2: Foster understanding of principles of viral immune evasion. By bringing together researchers from different viral systems in a program organized around concepts rather than viral families we seek to foster understanding of general principles. This should also clarify the important issue of what aspects of viral immune evasion are critical for the future of research in the area. Specific Aim 3: Provide an exciting environment for trainees and junior faculty. By providing a poster session and an opportunity for selected junior investigators, postdoctoral fellows, and students to present their work during the plenary sessions, we hope to heavily involve junior members of the community in the meeting. This should foster their career development.

病毒毒力是病毒生物学多个方面的结果，包括内在的生长速率，可传染性，细胞向性和组织对流。此外，当首先面对先天免疫反应，然后是适应性免疫时，病毒会面临重大障碍。作为响应，病毒具有抑制免疫激活或阻止免疫系统对抗感染的效应子的许多策略。免疫的贡献 逃避已有多年的认可，但在过去十年中仅通过机械细节进行了分析。在过去的十年中，这导致人们对病毒免疫逃避的理解显着增加。 ASM病毒免疫逃避会议旨在使世界上的顶级研究人员涉及病毒免疫逃避机制，以在这个快速前进的地区共享信息。我们有以下具体目标： 特定目的1：创建一个对病毒免疫逃避的兴趣的学者社区。由于许多调查人员邀请参加不同病毒系统的会议工作，因此不参加相同的会议，日程安排和发言人的选择旨在创建一个新的调查人员和受训者组，这些调查人员和受训者对病毒免疫逃避的共同兴趣。 特定目的2：促进对病毒免疫逃避原理的理解。通过将来自不同病毒系统的研究人员聚集在一个围绕概念而不是病毒家庭组织的计划中，我们寻求促进对一般原则的理解。这还应该阐明重要的问题，即逃避病毒免疫的哪些方面对于该地区的研究未来至关重要。 特定目标3：为学员和初级教师提供一个令人兴奋的环境。通过为选定的初级调查员，博士后研究员和学生提供在全体会议期间介绍他们的工作的机会，我们希望大量参与社区的初级成员参加会议。这应该促进他们的职业发展。