Admin Core - Autophagy Modulators as Novel Broad-Spectrum Anti-Infective Agents

管理核心 - 自噬调节剂作为新型广谱抗感染剂

基本信息

批准号：
10364722
负责人：
HERBERT W VIRGIN
金额：
$ 63.72万
依托单位：
UT SOUTHWESTERN MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-03-15 至 2024-02-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10364722
关键词：
Achievement Address Administrative Coordination Advisory Committees Animals Anti-Infective Agents Autophagocytosis Award Biology Cell Line Chemicals Collaborations Communication Communication Programs Complement Contracts Data Data Analyses Databases Ensure Evaluation Fostering Funding Generations Genes Goals Human Resources Individual Infrastructure Institution Laboratories Leadership Mediation Methodology National Institute of Allergy and Infectious Disease Participant Pathway interactions Preparation Process Progress Reports Quality Control Reagent Report (document)Reporting Research Research Activity Research Project Grants Resources Series Site Stream Teleconferences Therapeutic Time Travel United States National Institutes of Health base cohesion collaborative environment cost data exchange data sharing experimental study high throughput screening meetings member novel organizational structure priority pathogen programs therapeutic development therapeutic target

项目摘要

Project Summary – Administrative Core The Administrative Core will provide the requisite infrastructure to achieve the overall research objectives of the CETR. Effective scientific management and coordination by the Administrative Core will provide direction, oversight, and quality control for the research activities of each Project, and will maximize collaboration and exchange from all participating groups. Clear scientific leadership and direct communication by the Administrative Core will ensure optimal and transparent utilization of resources that promotes productive long- term relationships. The Administrative Core will promote data sharing, integration of projects, and communication, which will leverage the expertise of each member of the CETR to expedite discovery and achievement of the research goals. The Administrative Core will achieve several of these goals by providing a coherent stream of communication, which will begin by establishing monthly meetings between Program participants under the guidance of the Program Director. These meetings will be held through video teleconference and will promote data exchange, evaluation of progress and planning as it relates to the goals of the program and aims of individual projects. Each meeting will include discussion and analysis of results, goals and progress, as well as a forum for negotiation of key strategic decisions. The Administrative Core also will foster communication and organizational structure through preparation of financial reports and documents (e.g., progress reports) for the NIH. The Administrative Core will have specific financial responsibilities and obligations particularly as it relates to shared activities among CETR members. This will include costs associated with Scientific Advisory Committee travel and clerical/communication programs directly related to the CETR. Through these activities, the Administrative Core will ensure an interactive and collaborative environment, exchange of reagents and data, and foster a cohesive relationship among PIs of the CETR, which will enhance our direct goal of further developing novel autophagy-directed anti-infectives against NIAID priority pathogens.

项目摘要 - 行政核心行政核心将提供必要的基础架构，以实现 Cetr。行政核心的有效科学管理和协调将提供指导，对每个项目的研究活动的监督和质量控制，并将最大化协作和从所有参与团体进行交流。明确的科学领导和直接沟通行政核心将确保对资源的最佳和透明利用，从而促进生产性长期术语关系。行政核心将促进数据共享，项目集成以及沟通，这将利用CERTER的每个成员的专业知识加快发现和实现研究目标。行政核心将通过提供连贯的沟通流，这将从计划之间建立每月会议开始在计划主管的指导下的参与者。这些会议将通过视频举行电话会议并将促进数据交流，进度和计划的评估，因为它与目标有关单个项目的计划和目标。每次会议将包括讨论和分析结果，目标和进步，以及谈判关键战略决策的论坛。行政核心也将通过准备财务报告和文件来促进沟通和组织结构（例如 NIH的进度报告）。行政核心将承担特定的财务责任和义务特别是与CERT成员之间的共同活动有关。这将包括与科学咨询委员会旅行和文书/传播计划与CTR直接相关。通过这些活动，行政核心将确保互动和协作的环境，交流试剂和数据，并在CERTER的PI之间建立凝聚力的关系，这将增强我们的直接进一步开发针对NIAID优先病原体的新型自噬导向抗感染物的目标。