Drug Use & Latent Structure of Adolescent Mental Health

用药

• 批准号: 6876550
• 负责人: CARLA L STORR
• 金额: $ 24.53万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6876550
• 关键词: adolescence (12-20); age difference; aggression; behavioral /social science research tag; child behavior disorders; clinical research; data collection methodology /evaluation; drug abuse; gender difference; health surveys; human data; juvenile delinquency; peer group; racial /ethnic difference; social adjustment; substance abuse epidemiology

With cross-classification used to probe for possible male-female and child-adolescent variation, recently published evidence on the mental and behavioral disturbances of young people seems to confirm dimensional models of anxiety and depression (Wadsworth et al., 2001) as well as attention problems (Hudziak et al., 1999). In this new R01 project, the main goal is to investigate youth drug use as it relates to latent structure of mental and behavioral disturbances across age strata in adolescence (12-13,14-15,16-17 years), with due consideration for different drug types (inhalants; club drugs like ecstasy; marijuana; tobacco; alcohol) and levels of drug involvement. Once the underlying latent class structures have been elucidated, and class memberships have been assigned based on the best-supported class structures, the applicant will turn to regression models to probe research questions pertinent to (a) the co-occurrence of adolescent drug involvement and disturbances of the mental life, behavior, and social adaptation, (b) probing for variation in the latent structure across subgroups defined by race-ethnicity to perhaps aid in understanding health disparities that affect minority subgroups, and (c) the clustering of the class members within local areas of residence within the United States, with a specific focus upon analyses that will probe how drug use might sustain delinquent peer groups. The data are from 13,831 youths (age 12-17) recruited after nationally representative sampling for the National Household Survey on Drug Abuse (NHSDA) in 1994-1996. For the NHSDA, the youths completed standardized modules on drug involvement, as well as a survey adaptation of Achenbach's Youth Self Report (YSR). The YSR is perhaps, the most. widely used instrument for measuring youth disturbances in the mental life, behavior, and socxal adaptation. In sum, the plan of research is one that exploits an untapped research opportunity to learn more about adolescent drug taking as it relates to disturbances of the mental life, behavior, and social adaptation. The plan involves the use of two relatively recent biostatistical developments in the form of latent class regression and alternating logistic regression models, which are innovative approaches to the study of research questions that previously have not been asked in large-sample epidemiological studies of national scope.

用交叉分类用于探测可能的男女和儿童青春期的变化， 最近发表了有关年轻人的心理和行为障碍的证据，似乎证实了焦虑和抑郁症的维度模型（Wadsworth等，2001）以及注意力问题（Hudziak等，1999）。在这个新的R01项目中，主要目标是研究青年吸毒的使用，因为它与青春期跨年龄层的心理和行为障碍的潜在结构有关（12-13,14-15-15,16-17岁），并适当考虑不同的药物类型（inhalants;俱乐部;俱乐部毒品（例如狂热者），例如狂喜；大麻；托巴卡科；酒精）和药物含量。一旦阐明了潜在的潜在阶级结构，并且基于最佳支持的班级结构分配了阶级成员资格，即 applicant will turn to regression models to probe research questions pertinent to (a) the co-occurrence of adolescent drug involvement and disturbances of the mental life, behavior, and social adaptation, (b) probing for variation in the latent structure across subgroups defined by race-ethnicity to perhaps aid in understanding health disparities that affect minority subgroups, and (c) the clustering of the class members within local areas of residence within the United States,特别关注分析，这些分析将探讨药物使用如何维持犯罪同伴组。这些数据来自全国代表性滥用毒品滥用调查（NHSDA）（NHSDA）的13,831名年轻人（12-17岁） 1994-1996。对于NHSDA，年轻人完成了有关毒品参与的标准化模块，以及对Achenbach青年自我报告（YSR）的调查改编。 YSR也许是最多的。广泛使用的工具，用于衡量青年骚扰，行为和SOCXAL适应。总而言之，研究计划是利用尚未开发的研究机会，以了解有关青少年药物服用的更多信息，因为它与心理生活，行为和社会适应性的骚乱有关。该计划涉及使用潜在类别回归和交替的逻辑回归模型的两个相对较新的生物统计发展，这是研究研究问题的创新方法 以前在国家范围的大样本流行病学研究中尚未提出过要求。