Predoctoral Training Program in Developmental Biology

发育生物学博士前培训项目

• 批准号: 6894157
• 负责人: XING WANG DENG
• 金额: $ 37.7万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-29 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6894157
• 关键词: Predoctoral; Training; Program; Developmental; Biology

DESCRIPTION (provided by applicant): The proposed program will provide training of thirteen predoctoral students in developmental biology using all available modern approaches. This training program emphasizes six interdisciplinary areas: 1) organ system development; 2) development of model organisms; 3) model genetic systems (including Caenorhabitis, Drosophila, mouse, zebrafish, and Arabidopsis); 4) morphogenesis, cell shape and cell movement; 5) nucleic acid studies; and 6) developmental evolution. These development biology research areas bear on many aspects of molecular and cellular biology, genetics, and genomics. We believe that our integrated approach, using developmental genetic model systems in combination with multiple approaches, is particularly relevant. This is in light of the highly conserved nature of developmental regulatory systems, as well as the revolution of technologies useful for development biology research. The program is the only University-wide program in development biology, involving faculty from 3 departments in the Yale College of Arts and Sciences (FAS) and 6 departments/programs from the Yale School of Medicine. There are a total of 42 trainers in the program. Trainees are admitted to the Yale Graduate School by a Combined Program in the Biological and Biomedical Sciences (BBS). This admissions and training program has resulted in a steady increase in the size of the applicant pool, the yield, and the quality of pre-doctoral matriculants. The BBS also provides matriculants maximum flexibility in fashioning a personalized course of graduate studies leading to the PhD degree. Students may be appointed to the training program during their first, but more likely their second year. At all stages of training, the trainees are mentored by an advisor and an advisory committee, although, the composition of the advisors may change during progress toward graduation, especially after they advance to PhD candidacy. Trainees who enter this program will ordinarily hold at least a B.A. or B.S. degree in biology, biochemistry, chemistry, physics or related sciences. They will be selected on the basis of performance in undergraduate studies, letters of recommendation, GRE scores, and interviews. Students with strong potential for research will be sought. We will rely heavily on letters of recommendation and personnel interviews where feasible. After receiving the PhD degree, most of our trainees will spend two or more years in postdoctoral research, after which they take up positions as faculty members in medical schools, universities or colleges, or as research staff in medical centers, scientific research institutes, or biotech firms. The record of graduate students going on to run academic laboratories in development biology is historically strong and continues to be so. Graduate study in basic developmental research is today exciting and intellectually rewarding. The research is also satisfying and appealing, since it contributes increasingly to the solution of the human scourges such as birth defects, chronic diseases such as Alzheimer's and oncologies, and inadequate food production. For these reasons, the subject attracts top caliber students.

描述（由申请人提供）：拟议的计划将使用所有可用的现代方法为发育生物学的13名学生提供培训。该培训计划强调六个跨学科领域：1）器官系统开发； 2）模型生物的发展； 3）模型遗传系统（包括Caenorhabis，果蝇，小鼠，斑马鱼和拟南芥）； 4）形态发生，细胞形状和细胞运动； 5）核酸研究； 6）发展进化。这些发展生物学研究领域依靠分子和细胞生物学，遗传学和基因组学的许多方面。我们认为，使用发展遗传模型系统与多种方法结合使用，我们的综合方法尤其重要。鉴于发展监管系统的高度保守性，以及对开发生物学研究有用的技术的革命。该计划是唯一一项开发生物学的大学计划，涉及来自耶鲁大学艺术与科学学院（FAS）3个系的教职员工，以及耶鲁大学医学院的6个部门/计划。该计划中共有42名培训师。生物学和生物医学科学（BBS）的合并计划将受训人员录取耶鲁大学研究生院。该入学和培训计划导致申请人池的大小，产量和博士前母亲的质量稳步增加。 BBS还为培养一个个性化的研究生学习课程提供了最大的灵活性，从而获得了博士学位。学生可以在第一年期间任命学生参加培训计划，但更有可能是第二年。在培训的各个阶段，受训人员受到顾问和咨询委员会的指导，尽管顾问的组成可能会在毕业前进，尤其是在获得博士学位候选人资格之后。输入该计划的学员通常至少持有学士学位。或B.S.生物学，生物化学，化学，物理或相关科学学位。他们将根据本科学习，推荐信，GRE分数和访谈的表现进行选择。将寻求强大的研究潜力的学生。我们将在很大程度上依靠推荐信和可行的人事访谈。获得博士学位后，我们的大多数学员将在博士后研究中度过两年或更长时间，之后他们担任医学院，大学或大学的教职员工，或医学中心，科学研究机构或生物技术公司的研究人员。研究生在开发生物学领域的学术实验室的记录在历史上是很强的，并且仍然如此。如今，基本发展研究的研究生研究令人兴奋且具有智力上的回报。这项研究也令人满意和吸引人，因为它越来越多地解决了人类祸害，例如先天缺陷，慢性疾病，例如阿尔茨海默氏症和肿瘤学以及粮食生产不足。由于这些原因，该主题吸引了顶尖的学生。