Quantitative and Computational Biology Graduate Program

定量和计算生物学研究生课程

• 批准号: 6937218
• 负责人: DAVID BOTSTEIN
• 金额: $ 26.93万
• 依托单位: PRINCETON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-18 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6937218
• 关键词: Quantitative; Computational; Biology; Graduate; Program

DESCRIPTION (provided by applicant): Support is requested for a new multi-disciplinary training program in genomics at Princeton University, aimed at educating genome scientists with the quantitative and computational tools likely to be required for the biology of the future. The genome training program will support students in Princeton's new Graduate Program in Quantitative and computational Biology (QCB), a joint undertaking between the new Lewis-Sigler Institute for Integrative Genomics and four Princeton departments (Computer Science, Ecology and Evolutionary Biology, Molecular Biology, and Physics) and administered by the Institute. Genomics trainees will be able to do their thesis research with any of 54 QCB faculty in 10 departments united by common interests in quantitative and computational biology. Five genomics training slots are requested for the first year, 10 for the second, and 15 for each year thereafter, so that a steady-state population of 15 genomics trainees can be supported. In addition to fulfilling the requirements of one of the participating departments, genomics trainees will do research in any of a wide array of functional genomics projects in bacteria, eukaryotic models and mammalian systems; computational projects ranging from basic bio-informatics and molecular evolution to high-throughput data visualization; systems biology projects ranging from microbial metabolism to systems neuroscience; biophysical projects from basic structural biology to the construction of novel proteins and regulatory switches; and theoretical projects ranging from basic dynamical modeling to trying to model signal transduction in epithelia or neurons. Trainees will have an individualized training plan administered by the Executive Committee of the QCB and a Genomics Committee; formal training will include new courses in genomics and genomic analysis, a seminar series, a student-run journal club, and other multi-disciplinary activities centered in the Institute. Trainees will have the opportunity to teach in an innovative new multidisciplinary introductory program for undergraduates at Princeton. Finally, trainees and eligible faculty will participate in a number of activities designed to recruit and teach individuals who are members of under-represented minorities, and to extend the genomics message to high school teachers.

描述（由申请人提供）：请求支持普林斯顿大学基因组学的新的多学科培训计划，旨在教育基因组科学家，并使用未来生物学可能需要的定量和计算工具。基因组培训计划将支持普林斯顿新的定量和计算生物学研究生计划（QCB），这是新的刘易斯 - 西格勒综合基因组学研究所与四个普林斯顿部门（计算机科学，生态学和进化生物学，分子生物学和物理学）与研究所的联合。基因组学培训生将能够通过数量和计算生物学的共同利益与10个部门的54位QCB教师中的任何一个进行论文研究。第一年要求五个基因组学培训插槽，第二年为10个，此后每年为15个，以便支持15个基因组学员的稳态人群。除了满足参与部门之一的要求外，基因组学员还将在细菌，真核模型和哺乳动物系统中的各种功能基因组学项目中进行研究；计算项目范围从基本的生物信息学和分子进化到高通量数据可视化；系统生物学项目从微生物代谢到系统神经科学；从基本结构生物学到新型蛋白质和调节开关的结构的生物物理项目；以及从基本的动态建模到试图在上皮或神经元中建模信号转导的理论项目。学员将制定一个个性化的培训计划，由QCB执行委员会和基因组学委员会管理；正式培训将包括基因组学和基因组分析的新课程，研讨会系列，学生经营的期刊俱乐部以及以研究所为中心的其他多学科活动。学员将有机会在普林斯顿大学的本科生创新的新的多学科入门计划中进行教学。最后，学员和符合条件的教师将参加许多旨在招募和教导人数不足少数群体成员的活动，并将基因组学信息扩展到高中教师。