Core--Breeder and animal

核心——饲养员与动物

• 批准号: 7061695
• 负责人: Morton P Printz
• 金额: $ 30.81万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7061695
• 关键词: animal breeding; animal colony; biomedical facility; cryopreservation; genetic strain; laboratory rat; spontaneous hypertensive rat

This Core will continue to breed unique rat strains essential to the proposed studies of the Projects and which are available in the United States only from our colony. This Core will continue to breed and supply Program Investigators with the following strains: WKY/ Ij-cr, WKY/ Ij-tf, SHR/ Ij-cr, chromosome 2 congenics from a WKY/ Ij-cr X SHR/ Ij-cr cross, HXB-BXH Recombinant Inbred (RI) rat strains, SHR/Ola, BN.Lx, SHR.Lx and the PD/Cub rat. In addition, this Core will have responsibility for breeding additional intercross/backcross progeny or congenics as specified and requested by Projects. This Core will have oversight and review of all rat studies conducted in San Diego under this Program Project. This Core will assist Projects as requested and approved by the new Core B Advisory Committee.

该核心将继续培养针对该项目的拟议研究所必需的独特老鼠菌株，并且仅在我们的殖民地中才能在美国获得。该核心将继续为调查人员提供以下菌株：WKY/ IJ-CR，WKY/ IJ-TF，SHR/ IJ-CR，来自WKY/ IJ-CR X SHR/ IJ-CR Cross的2个染色体2相似，HXB-BXH重组（RI）大鼠菌株，SHR/OLA，BN.LX，SHR.LX和PD/CUB大鼠。此外，该核心将负责按照项目的指定和要求繁殖其他互变/反向后代或友善。该核心将对在该计划项目下在圣地亚哥进行的所有老鼠研究进行监督和审查。该核心将根据新核心B咨询委员会的要求和批准协助项目。