Pediatric Center--Gene Expression /Developmental Science

儿科中心--基因表达/发育科学

• 批准号: 6884027
• 负责人: THOMAS F BOAT
• 金额: $ 30.55万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-02-20 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6884027
• 关键词: biomedical facility; clinical research; epidemiology; gene expression; genome; genotype; growth /development; health science profession; health science research support; human subject; informatics; molecular biology; monoclonal antibody; nucleic acid sequence; pediatrics; protein purification; role model; statistics /biometry; training

DESCRIPTION (provided by applicant): This application is for continued funding for our Child Health Research Career Development Award (CHRCDA), which has established a unique center of excellence for the enhancement of basic and clinical research training in pediatrics with foci on molecular and cellular biology and clinical sciences. The center enhances the academic career development of junior pediatric faculty, providing mentorship and Core facilities designed to enhance the training of pediatricians as required for an academic career. The Center is integrated into established programs for research training: the Procter Scholar program and extensive NIH funded research programs. The program identifies and recruits promising junior pediatric faculty who complete a 2-3 year program for research enhancement within a CHRCDA program comprised of senior scientist mentors who share a central focus in molecular-cellular biology, molecular medicine or clinical sciences. Career development includes: 1) individual mentorship by Center staff investigators; 2) formal and informal training in molecular genetics and developmental biology, clinical research and epidemiology and an NIH-funded Clinical Research Center (CRC), and epidemiology and statistics; 3) Core research elements which will prioritize training in molecular biology, immunology, protein purification and transgenic models; and 4) Core research support for epidemiology and clinical research skills. The present application has drawn together established investigators with excellence in developmental science at the Children's Hospital and the University of Cincinnati College of Medicine. To meet our training goals, a four-part center is proposed: 1) Center Staff Investigators who share interest and expertise in the application of molecular and cellular biology and informatics technology in the study of mammalian development, molecular medicine, and clinical research serve as primary mentors for the Pediatrician-Scholars; 2) The Administrative Core identifies recruits, and monitors the overall training of the Pediatrician-Scholars. The Core provides support for national recruitment efforts at local and national levels and prioritizes minority recruitment; 3) Research Cores facilitate the application of molecular and cellular biology and clinical research/epidemiology and statistics to the research programs of Pediatrician-Scholars. Research Core elements include Molecular Biology Cores, informatics support, clinical research study design support and Transgenic Mouse Cores. Other Cores available include Hybridoma, Protein Analysis, Molecular Morphology, Gene Array Informatics, and Study Design, which will provide both training and technical assistance. 4) Research support grants provide the Pediatrician-Scholar research funds and mentorship for a period of up to three years. This combined program of individual mentorship and advanced training in contemporary molecular, cellular, developmental biology and clinical sciences enhances the training and research productivity of our Pediatrician-Scholars as they begin highly productive academic careers in pediatric science.

描述（由申请人提供）：此申请适用于续 为我们的儿童健康研究职业发展奖（CHRCDA）提供资金，该奖 已经建立了一个独特的卓越中心，以增强基础和 小儿研究的临床研究培训，重点是分子和细胞 生物学和临床科学。 该中心增强了学术职业 开发初级小儿教师，提供指导和核心 旨在根据需要增强儿科医生培训的设施 学术生涯。 该中心被整合到已建立的计划中 研究培训：宝洁学者计划和广泛的NIH资助 研究计划。 该计划确定和新兵有希望的初级 小儿教师完成了2 - 3年的研究增强计划 在CHRCDA计划中，由高级科学家导师组成，他们共享 分子细胞生物学，分子医学或临床的中心重点 科学。 职业发展包括：1）中心的个人指导 工作人员调查员； 2）分子遗传学和非正式培训和非正式培训 发育生物学，临床研究和流行病学以及NIH资助 临床研究中心（CRC）以及流行病学和统计； 3）核心 研究元素将优先考虑分子生物学的培训， 免疫学，蛋白质纯化和转基因模型； 4）核心研究 支持流行病学和临床研究技能。 现在 申请已吸引了卓越的成熟调查员 儿童医院和大学的发展科学 辛辛那提医学院。 为了满足我们的训练目标，四部分 建议中心：1）共享利益和的中心工作人员调查员 分子和细胞生物学和信息学应用方面的专业知识 哺乳动物发展，分子医学和 临床研究是儿科医生chol的主要导师。 2） 行政核心确定新兵，并监视整体培训 小儿chol。 核心为国家提供支持 在地方和国家一级的招聘工作，并优先考虑少数民族 招聘; 3）研究核心促进分子和 细胞生物学和临床研究/流行病学和统计学 小儿chol的研究计划。 研究核心元素包括 分子生物学核心，信息学支持，临床研究设计 支撑和转基因小鼠核。 可用的其他核心包括杂交瘤 蛋白质分析，分子形态，基因阵列信息学和研究 设计，将提供培训和技术帮助。 4） 研究支持赠款提供儿科医生研究基金和 指导长达三年。 这个组合的程序 个人指导和当代分子的高级培训， 细胞，发育生物学和临床科学增强了训练 以及我们的儿科医生 - 开始的生产力高度开始 小儿科学的生产学术职业。