Improving soft-tissue contrast of cone beam CT

提高锥形束CT软组织对比度

• 批准号: 7039224
• 负责人: Predrag Sukovic
• 金额: $ 36.61万
• 依托单位: XORAN TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-03-28 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7039224
• 关键词: bioimaging /biomedical imaging; biomedical equipment development; computed axial tomography; craniofacial; dental visualization; human tissue; image enhancement; imaging /visualization /scanning; mandible /maxilla

DESCRIPTION (provided by applicant): Xoran Technologies has developed a dedicated, in-office, dentomaxillofacial cone-beam CT (CBCT) scanner through previous grants from the National Institute of Health. The scanner, formerly dubbed DentoCAT, has been recently FDA approved and is currently being marketed under the name i-CAT through a partnership between Xoran Technologies and Imaging Sciences International. The scanner has met with an exceptionally high market adoption, with over twenty five orders taken in the first three months of marketing. As of the time of the writing of this grant, three units have been installed, with the rest scheduled for the upcoming weeks. While the scanner produces images with high spatial resolution and is well-suited to relatively high contrast imaging tasks, its current capability for low contrast imaging is limited. The same can be said for other commercially available dedicated dentomaxillofacial cone beam CT scanners. The ultimate goal of this project is to improve the capability of cone-beam CT technology to image low-contrast features. This will allow for the i-CAT system to be used in a broader range of dentomaxillofacial diagnostic situations including the detection and localization of soft-tissue lesions like cysts, tumors, and infections. We see cone-beam artifacts as a major challenge in achieving the improved soft tissue contrast throughout the entire image volume and have for that reason chosen to focus on eliminating these artifacts in Phase I of this effort.

描述（由申请人提供）：Xoran Technologies 通过美国国立卫生研究院之前的资助，开发了一款专用的办公室内牙颌面锥形束 CT (CBCT) 扫描仪。该扫描仪以前称为 DentoCAT，最近已获得 FDA 批准，目前通过 Xoran Technologies 和 Imaging Sciences International 合作以 i-CAT 名称进行销售。该扫描仪获得了极高的市场采用率，在上市的前三个月就收到了超过 25 个订单。截至撰写本赠款时，已安装三个单元，其余单元计划在未来几周内安装。虽然扫描仪产生高空间分辨率的图像并且非常适合相对高对比度的成像任务，但其当前的低对比度成像能力有限。对于其他市售专用牙颌面锥形束 CT 扫描仪来说也是如此。该项目的最终目标是提高锥束CT技术对低对比度特征的成像能力。这将使 i-CAT 系统能够用于更广泛的牙颌面诊断情况，包括囊肿、肿瘤和感染等软组织病变的检测和定位。我们认为锥束伪影是在整个图像体积中实现改善的软组织对比度的主要挑战，因此选择在这项工作的第一阶段重点消除这些伪影。