Structural Genomics

结构基因组学

• 批准号: 6747806
• 负责人: Stephen Kevin Burley
• 金额: $ 0.3万
• 依托单位: KEYSTONE SYMPOSIA
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-02-01 至 2005-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6747806
• 关键词: X ray crystallography; functional /structural genomics; meeting /conference /symposium; nuclear magnetic resonance spectroscopy; protein structure; travel

DESCRIPTION (provided by applicant): The goal of the 2004 Keystone Structural Genomics Meeting is to provide a venue for discussion of progress, technical advances, and challenges in the field. Keynote and invited speakers are all thought leaders in the areas of Bioinformatics/Target Selection, Protein Expression/Purification, Sample Preparation, X-ray Crystallography, Solution NMR Spectroscopy, Electron and Light Microscopy, Mass Spectrometry, Data Analysis, Functional Annotation, and Structure-Based Drug Discovery. Keynote and Regular Sessions cover the following topics: * Selection of targets that both increase our knowledge of protein structure and enhance biomedical research. * High-throughput sample preparation for solution NMR spectroscopy and X-ray crystallography. * Automated data reduction, structure determination, refinement, and data deposition. * Approaches to functional annotation of new protein structures. * The impact of high-throughput structural studies of protein-ligand complexes in drug discovery. Four Poster Sessions provide ample opportunity for presentations of work by conferees, particularly Younger Scientists. Four additional afternoon workshops include: (1) Graduate Student/Postdoctoral presentations selected from Poster Abstracts. (2) Presentations from representatives of foreign and domestic agencies funding structural genomics initiatives. (3) Progress Reports from Structural Genomics Centers in the United States. (4) Progress Reports from Structural Genomics Centers in Canada, South America, Europe, and Asia. This meeting includes significant participation from industrial speakers, and is expected to attract large numbers of scientists from both academe and industry. Systematic efforts have been made to include Female, Minority, and Physically Challenged Speakers. Finally, this meeting is being held in conjunction with the 2004 Keystone Structural Biology Meeting, and features three joint sessions (including the Keynote).

描述（由申请人提供）：2004年Keystone结构基因组学会议的目标是为该领域的进度，技术进步和挑战提供讨论的场所。 主题演讲者和受邀演讲者都是生物信息学/目标选择，蛋白质表达/纯化，样品制备，X射线晶体学，溶液NMR光谱，电子和光显微镜，质谱，数据分析，功能注释和结构的思想。基于基于药物发现。 主题演讲和常规会议涵盖以下主题： *选择既可以提高我们对蛋白质结构的了解并增强生物医学研究的目标。 *溶液NMR光谱和X射线晶体学的高通量样品制备。 *自动数据减少，结构确定，改进和数据沉积。 *新蛋白质结构功能注释的方法。 *蛋白质配体复合物在药物发现中的高通量结构研究的影响。 四个海报会议为Conterees的工作提供了充足的机会， 特别是年轻的科学家。 另外四个下午讲习班包括： （1）从海报摘要中选择的研究生/博士后演讲。 （2）外国和国内机构代表资助结构基因组学计划的演讲。 （3）美国结构基因组学中心的进度报告。 （4）来自加拿大，南美，欧洲和亚洲的结构基因组中心的进度报告。 这次会议包括工业发言人的大量参与，有望 吸引来自学术界和工业的大量科学家。 已经做出了系统的努力，包括女性，少数群体和身体挑战 演讲者。 最后，这次会议与2004 Keystone结构生物学结合 会议，并举办三个联合会议（包括主题演讲）。