Non Contacting Bioelectric Array for Sleep Monitoring

用于睡眠监测的非接触式生物电阵列

• 批准号: 6741707
• 负责人: ROBERT MATTHEWS
• 金额: $ 9.99万
• 依托单位: QUASAR, INC.
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2005-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6741707
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; biosensor device; clinical research; electrocardiography; electroencephalography; electromyography; electrooculography; human subject; microelectrodes; noninvasive diagnosis; patient monitoring device; polysomnography; sleep; sleep disorders

DESCRIPTION (provided by applicant): The goal of this program is to develop a non-contacting array of bioelectrodes for monitoring EEG, EOG, EMG and ECG on the head. By non-contacting we mean that the bioelectrodes are not in contact with the skin but can be separated by a small air gap, or located on the outer surface of a cap or patch worn by the patient. The proposed new system builds on a new class of sensor that can measure the electric potential of free-space at the microvolt level. A September 2002 clinical trial showed that when operating through a cotton shirt small bioelectrodes based on the new sensor have > 99% correlation with a conventional skin contact electrode. The aims of this program are to study and overcome artifacts associated with using these sensors in close proximity to the head, to develop a complete system for sleep monitoring using the minimum number of sensors, and to test the technology in the Sleep Research Laboratory at Stanford University. The proposed bioelectrode array is completely new and offers a new modality for standoff measurement of physiologic signals, providing the capability to work with minimal or no skin preparation, and increased safety (the electrodes do not make electrical contact). It should be possible to build the electrodes onto the outside of a cap or shirt to provide greatly increased comfort and wearability. The system would provide a major improvement in comfort for sleep studies, providing minima disturbance to the patient and the capability for long term at-home monitoring. In addition, the new system will also find wide application in many other areas of clinical care that involve long and short term monitoring of ECG, EEG, and EMG signals, and should make possible a new of new systems for outpatient monitoring. Potential applications include research and clinical instrumentation for sleep monitoring, systems for at-home monitoring of sleep, continuous physiologic monitoring of EEG and ECG activity, non-contact bioelectrodes for burn victims, rapidly applied ECG detectors for emergency response teams, and self-applied ECG sensors for home care. Further opportunities should exist in alertness monitoring, sporting equipment, and video games.

描述（由申请人提供）： 该项目的目标是开发一种非接触式生物电极阵列，用于监测头部脑电图、眼电图、肌电图和心电图。非接触式是指生物电极不与皮肤接触，但可以通过小气隙隔开，或者位于患者佩戴的帽子或贴片的外表面上。 拟议的新系统建立在新型传感器的基础上，可以测量微伏级自由空间的电势。 2002 年 9 月的一项临床试验表明，当通过棉衬衫进行操作时，基于新型传感器的小型生物电极与传统皮肤接触电极的相关性超过 99%。该计划的目的是研究和克服与在头部附近使用这些传感器相关的伪影，使用最少数量的传感器开发完整的睡眠监测系统，并在斯坦福大学睡眠研究实验室测试该技术大学。 所提出的生物电极阵列是全新的，为生理信号的远距离测量提供了一种新的方式，提供了在最少或无需皮肤准备的情况下工作的能力，并提高了安全性（电极不进行电接触）。应该可以将电极安装在帽子或衬衫的外侧，以大大提高舒适度和耐磨性。该系统将大大提高睡眠研究的舒适度，对患者的干扰最小化，并能够进行长期家庭监测。此外，新系统还将广泛应用于涉及心电图、脑电图和肌电图信号的长期和短期监测的许多其他临床护理领域，并且应该使门诊监测的新系统成为可能。 潜在应用包括用于睡眠监测的研究和临床仪器、家庭睡眠监测系统、脑电图和心电图活动的连续生理监测、烧伤患者的非接触式生物电极、紧急响应小组的快速应用心电图探测器以及自我应用用于家庭护理的心电图传感器。警觉性监测、运动器材和视频游戏领域应该存在更多机会。