Behavior & Clinical Trials Participation in HIV+ Latinos

行为

• 批准号: 6947611
• 负责人: Maria Luisa Zuniga de Nuncio
• 金额: $ 12.18万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-25 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6947611
• 关键词: HIV infections; Hispanic Americans; adolescence (12-20); adult human (21+); behavioral /social science research tag; clinical research; clinical trials; data collection methodology /evaluation; focus groups; health behavior; health care service utilization; health surveys; human population study; human subject; information dissemination; interview; patient oriented research; social model

DESCRIPTION (provided by applicant): Through this research career development award, I will complete the initial steps to establish myself as an independent researcher in HIV/AIDS behavioral research to reduce health disparities in Latino communities infected with HIV. Using didactic and mentored learning, I will improve upon my existing behavioral, qualitative, and quantitative research skills to address the issue of low participation in HIV/AIDS clinical trials in Latino communities. Proportionate representation of minority populations in research trials is necessary to improve research capacity to generalize results to diverse populations infected with HIV. My specific research aims are to: 1) Describe and understand the attitudes, beliefs, cultural and social norms, provider and system influences relating to entry into clinical trials in HIV+ Mexican-origin Latinos, and 2) Develop and pilot test an intervention for improving understanding and acceptance of HIV clinical trials participation by HIV+ Mexican-origin Latinos and their communities. The theoretical framework of the research plan is the Behavioral Model of Health Services Use (Andersen, Aday, et al.). The research plan will be carried out in three phases, each phase linked to a career development objective and activity. In Phase 1 I will conduct formative research using qualitative methods with HIV+ Mexican-origin Latinos, including design and implementation of an in-depth interview protocol and focus group questions to explore factors to consider in attempting to improve clinical trials participation in Latino populations. In Phase 2 I will carry out qualitative analysis, develop a social cognitive model of participation in research, develop research hypotheses, and develop and pilot test a survey to test the social cognitive model in HIV+ Mexican-origin Latinos. In Phase 3 I will validate the survey, analyze and report outcomes, design and pilot-test a behavioral intervention to increase clinical trials participation in HIV+ Mexican-origin Latinos, and finally, use intervention pilot data to prepare an R01 proposal to the NIH to promote participation of HIV+ Latinos in clinical trials.

描述（由申请人提供）：通过本研究职业发展奖，我将完成最初的步骤，以确立自己为艾滋病毒/艾滋病行为研究的独立研究人员，以减少受艾滋病毒感染的拉丁裔社区的健康差异。使用教学和指导的学习，我将改进我现有的行为，定性和定量研究技能，以解决较低参与拉丁裔社区艾滋病毒/艾滋病临床试验的问题。在研究试验中，必须对少数群体的比例表示，以提高研究能力，以将结果推广到感染HIV的不同种群。我的具体研究目的是：1）描述和理解与进入HIV+墨西哥 - 原始拉丁裔临床试验有关的态度，信念，文化和社会规范，提供者和系统的影响，以及2）开发和试点测试，用于改善HIV HIV临床试验参与HIV+ Mexican-Mexican-Mexican-Origin-origin-origin-origin-origin和他们的社区的干预措施，以改善HIV临床试验。研究计划的理论框架是卫生服务使用的行为模型（Andersen，Aday等）。研究计划将分为三个阶段，每个阶段都与职业发展目标和活动有关。在第1阶段，我将使用具有HIV+墨西哥 - 原始拉丁裔的定性方法进行形成性研究，包括设计和实施深入的访谈协议和焦点小组问题，以探索试图改善临床试验参与拉丁裔人群的因素。在第2阶段，我将进行定性分析，开发参与研究的社会认知模型，开发研究假设，并开发和试点测试一项调查，以测试HIV+墨西哥 - 原始拉丁裔的社会认知模型。在第3阶段，我将验证调查，分析和报告结果，设计和试点测试行为干预措施，以增加临床试验参与HIV+墨西哥 - 原始拉丁美洲人的参与，最后，使用干预试验数据为NIH准备R01提案，以促进HIV+ Latinos参与临床试验。