Novel Protective Underglove

新型防护内衣

• 批准号: 6766967
• 负责人: BAKUL M BHATT
• 金额: $ 39.94万
• 依托单位: BIOMEDICAL DEVELOPMENT CORPORATION
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6766967
• 关键词: biohazard control; biomaterial development /preparation; clinical biomedical equipment; clinical research; human subject; nosocomial infection control; polyvinyls; safety equipment; surgery material /equipment; user protection

DESCRIPTION (provided by applicant): The goal of this project is to complete the development of a unique, non-toxic thin film technology to be used as a skin barrier that is worn underneath surgical and examination gloves. The efficacy of gloves has become an important issue, especially for healthcare workers where exposure to blood or other body fluids is frequent. This technology has been developed to reduce transmission of bacteria and bloodborne pathogens. Glove punctures are frequent, and the potential for pathogen transmission is increasingly significant. Additionally, with the heightened awareness of bloodborne pathogens, the use of exam gloves has increased. The proposed technology can provide skin protection from the detrimental effects of chronic glove wearing and hand washing. The following Phase II studies have been designed to complete the development of this novel underglove technology: 1) implementation of Good Manufacturing Practices (GMP) and establishment of packaging, 2) evaluation of coating formulations for effects on skin physiology, and 3) demonstration of the safety of coatings in human safety studies.

描述（由申请人提供）： 该项目的目的是完成一种独特的无毒薄膜技术的开发，该技术将用作外科手术和检查手套下的皮肤屏障。手套的功效已成为一个重要的问题，尤其是对于经常暴露于血液或其他体液的医护人员而言。已开发该技术来减少细菌和血源性病原体的传播。手套穿刺是频繁的，病原体传播的潜力越来越重要。此外，随着对血源性病原体的认识的提高，使用检查手套的使用增加了。提出的技术可以提供皮肤保护，从而免受慢性手套戴和洗手的不利影响。以下第二阶段的研究旨在完成这种新型底层技术的开发：1）实施良好的制造实践（GMP）和包装的建立，2）评估涂层配方对皮肤生理的影响，3）证明了人类安全研究中涂层安全性。